妇炎康丸治疗湿热内蕴型急性盆腔炎临床研究  

Clinical Study on Fuyankang Pills for Acute Pelvic Inflammation of Internal Dampnessheat Retention Type

作　　者：王春琴 余佩英 WANG Chunqin;YU Peiying

机构地区：[1]淳安县妇幼保健院,浙江淳安311700

出　　处：《新中医》2020年第9期89-91,共3页New Chinese Medicine

摘　　要：目的:观察妇炎康丸联合替硝唑注射液治疗湿热内蕴型急性盆腔炎的临床疗效及其对血液流变学、炎症因子水平的影响。方法:将88例患者随机分为对照组和试验组,每组44例;对照组给予替硝唑注射液静脉滴注;试验组在对照组的基础上加用妇炎康丸口服;观察比较2组患者体温复常、白细胞复常情况,以及血液流变学、炎症因子[白细胞介素-2(IL-2)、降钙素原(PCT)、肿瘤坏死因子α(TNF-α)、γ干扰素(IFN-γ)]水平变化,并统计2组临床疗效。结果:总有效率试验组为90.9%,对照组为70.5%,2组比较,差异有统计学意义(P<0.05)。治疗后,体温复常率、白细胞计数复常率试验组分别为93.2%、86.4%,对照组分别为75.0%、61.4%,2组比较,差异均有统计学意义(P<0.05)。治疗后,2组患者全血黏度(中切)、血浆黏度均较治疗前明显下降(P<0.05);且试验组2项指标均明显低于对照组(P<0.05)。治疗后,2组患者PCT、TNF-α、IFN-γ水平均较治疗前明显降低(P<0.05),且试验组各项指标均明显低于对照组(P<0.05)。结论:妇炎康丸联合替硝唑注射液治疗湿热内蕴型急性盆腔炎疗效肯定,可有效下调患者炎症因子水平,改善血液流变学状态,值得临床推广应用。Objective:To observe the clinical effect of Fuyankang pills combined with tinidazole injection for acute pelvic inflammation of internal dampness-heat retention type and its effect on the levels of hemorheology and inflammatory factors.Methods:A total of 88 cases of patients were randomly divided into the control group and the experiment group,44 cases in each group.The control group was given tinidazole injection by intravenous drip,and the experiment group was additionally given oral administration of Fuyankang pills based on the treatment of the control group.The conditionof temperature and leukocyte to return to normal,and the changes in the levels of hemorheology and inflammatory factors including interleukin-2(IL-2),procalcitonin(PCT),tumor necrosis factor-α(TNF-α)and interferon-γ(IFN-γ)in the two groups were observed and compared.The clinical effect in the two groups was counted.Results:The total effective rate was 90.9%in the experiment group,and 70.5%in the control group,the difference being significant(P<0.05).After treatment,the normalization rates of temperature and leukocyte were respectively 93.2%and 86.4%in the experiment group,and respectively 75.0%and 61.4%in the control group,differences being significant(P<0.05).After treatment,the blood viscosity and the one of medium shear in the two groups were significantly decreased when compared with those before treatment(P<0.05);the above two indexes in the experiment group were significantly lower than those in the control group(P<0.05).After treatment,the levels of PCT,TNF-αand IFN-γin the two groups were significantly decreased when compared with those before treatment(P<0.05),and the above three levels in the experiment group were significantly lower than those in the control group(P<0.05).Conclusion:The therapy of Fuyankang pills combined with tinidazole injection has defined curative effect in treating patients with acute pelvic inflammation of internal dampness-heat retention type,effectively down-regulating their levels of inflammatory fac

关 键 词：急性盆腔炎 湿热内蕴 妇炎康丸 替硝唑注射液 炎症因子 血液流变学 

分 类 号：R711.33[医药卫生—妇产科学]