过渡金属催化炔丙基胺的合成研究  

Study on the Synthesis of Propargylamine Catalyzed by Transition Metal

作　　者：楚惠元 李晓杰[1] 高子舒[1] 张文博[1] CHU Hui-yuan;LI Xiao-jie;GAO Zi-shu;ZHANG Wen-bo(Department of Ecological Resources and Engineering of Hetao College,Bayannur 015000,China)

机构地区：[1]河套学院生态资源与工程系,内蒙古巴彦淖尔015000

出　　处：《化工管理》2020年第16期73-74,81,共3页Chemical Engineering Management

基　　金：河套学院科学技术研究项目资助;项目类别:自然科学青年项目;项目编号:HYZQ201405。

摘　　要：文章主要介绍了由过渡金属溴化亚铜催化合成二茂铁基炔丙基胺的研究。以溴化亚铜为催化剂,1,4-二氧六环为溶剂,吗啡啉、苯甲醛、二茂铁乙炔、为反应底物,回流搅拌反应得到目标产物。通过薄层色谱法(TLC)跟踪反应进行程度。确定反应完成后,经过柱层析,分离、纯化得到目标产物。然后采用傅里叶红外光谱仪对产物结构的特征红外吸收峰进行了表征,基本上可以确定产物结构的正确性。This article mainly introduces the study on the synthesis of ferrocene-propargylamine from transition metal cuprous bromide.With cuprous bromide as the catalyst,1,4-dioxane as the solvent,morpholine,benzaldehyde,and ethynylferrocene as the reaction substrate,the reaction was stirred at reflux to obtain the target product.The progress of the reaction was followed by thin layer chromatography(TLC).After confirming the completion of the reaction,the target product was isolated and purified by column chromatography.Then the characteristic infrared absorption peaks of the product structure were characterized by Fourier infrared spectrometer,and the correctness of the product structure was basically determined.

关 键 词：二茂铁乙炔 溴化亚铜 炔丙基胺 合成 

分 类 号：TQ226.31[化学工程—有机化工]