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作 者:咸楠星 张哲[1,2] 李宁[1] 刘楠[1,2] XIAN Nanxing;ZHANG Zhe;LI Ning;LIU Nan(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)
机构地区:[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032
出 处:《中华中医药学刊》2020年第4期20-24,共5页Chinese Archives of Traditional Chinese Medicine
基 金:国家自然科学基金(8204100052);教育部中医脏象理论与应用重点实验室项目([2014]348)。
摘 要:从病毒可能的感染过程与温病传变规律,探讨血管紧张素酶2(angiotensin-converting enzyme 2,ACE2)在病毒感染的受体作用与相关功能失调与肺祖细胞损伤造成的凝血功能障碍引起重症肺炎的可能机制,并依据中医经典理论分析重症形成原因与规律,结合相关指南提供相应中西医结合的防治方法建议与为中西医结合治疗传染病提出创新性建议与新药的研发提供思路。This article discussed the possible mechanism of severe pneumonia caused by the receptor action of ACE2 in virus infection and the related dysfunction of blood clotting caused by pulmonary progenitor cell injury and analyzed the severe pneumonia formation rule according to the classical theory of traditional Chinese medicine. And according to the relevant guidelines,it provided the corresponding integrated Chinese and Western medicine prevention and treatment of infectious diseases as well as the innovative advice for integrated Chinese and Western medicine treating infectious diseases. It also can provide ideas for new drug research and development.
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