补肾调经汤对多囊卵巢综合征卵巢超声影像学改变及预后的影响  

Effect of Bushen Tiaojing Decoction on Ultrasonographic Imaging Changes and Prognosis of Patients with Polycystic Ovary Syndrome

作　　者：黎才洋 王乐华[1] 张若 LI Caiyang;WANG Lehua;ZHANG Ruo(Department of Ultrasound,The Second Affiliated Hospital of Hainan Medical College,Haikou 570000,Hainan,China;Department of Obstetrics and Gynecology,The Second Affiliated Hospital of Hainan Medical College,Haikou 570000,Hainan,China)

机构地区：[1]海南医学院第二附属医院超声科,海南海口570000 [2]海南医学院第二附属医院妇产科,海南海口570000

出　　处：《中华中医药学刊》2020年第4期72-75,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家中医药管理局中医药行业科研项目(2015080044);海南省自然科学基金(SQ2015ZRJJ0264)。

摘　　要：目的探究补肾调经汤对多囊卵巢综合征患者卵巢超声影像学改变及预后的影响。方法选择2016年3月-2017年12月于医院诊断多囊卵巢综合征的84例患者作为研究对象,采用随机数表法将患者分为两组各42例,为观察组和对照组。对照组行常规西药治疗,观察组在西药治疗的基础上加补肾调经汤。以两个月为一个疗程,比较两组治疗前的卵巢改善情况、卵巢间质动脉血流参数情况、临床疗效及不良反应情况,并随访1年比较两组患者预后排卵与妊娠情况。结果治疗后两组的卵巢体积和卵泡数量均明显降低,观察组的更低,其差异显著,有统计学意义(P<0.05)。治疗后两组患者的卵巢间质动脉血流搏动指数(PI)、阻力指数(RI)均明显升高,收缩期峰值血流速度(PSV)、舒张末期血流速度(EDV)均明显下降,观察组变化更显著,其差异有统计学意义(P<0.05)。观察组总有效率为88.10%(37/42),治愈率为42.86%(18/42),高于对照组,观察组不良反应率为4.76%(2/42),低于对照组的16.67%(7/42),其差异明显,有统计学意义(P<0.05)。观察组的排卵率、妊娠率分别为83.33%(35/42)、57.14%(24/42),高于对照组61.90%(26/42)、30.95%(13/42),其差异显著,有统计学意义(P<0.05)。结论补肾调经汤治疗多囊卵巢综合征的疗效显著,可明显改善患者的卵巢状况及其间质动脉血流状况,且不良反应少,更为安全,预后效果更好,值得临床推广应用。Objective To explore the effect of Bushen Tiaojing Decoction on ovarian ultrasound imaging changes and prognosis in patients with polycystic ovary syndrome.Methods Eighty-four patients with polycystic ovary syndrome diagnosed in hospital from March 2016 to December 2017 were enrolled in the study. The patients were divided into two groups by the random number table method, which were the observation group and the control group. The control group received routine Western medicine intervention, and the observation group added Bushen Tiaojing Decoction on the basis of western medicine treatment. Two months was a course of treatment. The ovarian improvement, ovarian interstitial blood flow parameters, clinical efficacy and adverse reactions were compared between the two groups. The prognosis of ovulation and pregnancy condition were compared between the two groups. Results After treatment, the ovarian volume and number of follicles in the two groups were significantly lower, and the observation group’s was lower and the difference was statistically significant(P<0.05). After treatment, the ovarian interstitial blood flow index(PI) and resistance index(RI) of the two groups were significantly increased, and the peak systolic blood flow velocity(PSV) and end-diastolic blood flow velocity(EDV) were significantly decreased. The changes in the observation group were more significant, and the difference was statistically significant(P<0.05). The total effective rate of the observation group was 88.10%(37/42), and the cure rate was 42.86%(18/42), which was higher than that of the control group. The adverse reaction rate of the observation group was 4.76%(2/42), which was lower than that of the control group(16.67%). The difference was statistically significant(P<0.05). The ovulation rate and pregnancy rate of the observation group were 83.33%(35/42) and 57.14%(24/42), respectively, which were higher than 61.90%(26/42) and 30.95%(13/42) of the control group, and the difference was statistically significant(P<0.05). Conclus

关 键 词：补肾调经汤 多囊卵巢综合征 预后 彩色多普勒 

分 类 号：R271.911.75[医药卫生—中西医结合]