层次分析法多指标正交实验优选葛根解酒方的提取工艺  

Optimization of Extraction Process of Gegen Jiejiu Recipe Based on Analytic Hierarchy Process and Multi Index Orthogonal Experiment

作　　者：张彩光 周灿 王佳 胡晓 石金敏 ZHANG Cai-guang;ZHOU Can;WANG Jia;HU Xiao;SHI Jin-min(School of Pharmacy,Hubei University of Medicine;Department of Pharmacy,Renmin Hospital,Hubei University of Medicine,Shiyan,Hubei 442000,China)

机构地区：[1]湖北医药学院药学院,湖北十堰442000 [2]十堰市人民医院·湖北医药学院附属人民医院药学部,湖北十堰442000

出　　处：《湖北医药学院学报》2020年第2期114-117,共4页Journal of Hubei University of Medicine

基　　金：十堰市科学技术研究与开发项目(16Y36,16Y40);湖北省高等学校省级大学生创新创业训练计划项目(201810929064);湖北医药学院学生科研基金资助(201810929064)。

摘　　要：目的:优选葛根解酒方的最佳提取工艺。方法:采用正交实验法,以葛根素和大豆苷为指标,通过层次分析法(analytic hierarchy process,AHP)确定权重,多指标综合评分优选葛根解酒方的工艺参数。结果:处方药材加10倍量水,提取3次,每次1.5 h。结论:运用AHP法确定权重系数,优选得到的工艺稳定可行,可用于工业化生产。Objective To establish an optimized extraction process for Gegen Jiejiu recipe.Methods The weight of puerarin and daidzein was determined by analytic hierarchy process(AHP),and the technological parameters of Gegen Jiejiu recipe were optimized by multi index comprehensive score.Results The prescription medicinal materials were added with 10 times amount of water,extracted 3 times,each time 1.5 hours.Conclusion Using AHP method to determine the weight coefficient,the optimized process is stable and feasible,and It can be used in industrial production.

关 键 词：葛根解酒方 层次分析法 正交实验 提取工艺 

分 类 号：R283.6[医药卫生—中药学]