点阵激光联合卤米松乳膏透皮给药治疗增生性瘢痕的疗效  

Efficacy of lattice laser combined with transdermal administration of halomethasone in treating hyper-trophic scars

作　　者：杜鑫[1] 杨春俊[1] Du Xin;Yang Chunjun(Department of Dermatology,the Second Affiliated Hospital of Anhui Medical University,Hefei 230001,China)

机构地区：[1]安徽医科大学第二附属医院皮肤性病科,合肥230001

出　　处：《中华医学美学美容杂志》2020年第2期142-144,共3页Chinese Journal of Medical Aesthetics and Cosmetology

基　　金：安徽省科技攻关课题(1704a0802147)。

摘　　要：目的探讨点阵激光联合卤米松乳膏透皮给药治疗增生性瘢痕的有效性及安全性.方法2014年1月至2019年12月,安徽医科大学第二附属医院皮肤性病科门诊增生性瘢痕患者123例.观察组63例,男30例,女33例;年龄7~69(31.7±14.6)岁;给予卤米松乳膏外用,早晚各1次,联合点阵激光透皮给药,每周1次,疗程3个月.对照组60例,男28例,女32例;年龄10~71(32.8±15.1)岁;给予卤米松乳膏外用,早晚各1次,疗程3个月.结果123例患者均完成临床试验.观察组有效率66.7%(42/63例),其中痊愈18例,显效18例;有效6例,无效21例;对照组有效率20.0%(12/60例),其中痊愈0例,显效7例,有效5例,无效48例.观察组有效率明显优于对照组(P<0.05),观察组无不良反应.结论点阵激光透皮给药联合卤米松乳膏外用治疗增生性瘢痕疗效明显、安全.Objective To investigate the safety and effectiveness of dot matrix laser combined with transdermal administration in the treatment of hypertrophic scars.Methods From January 2014 to December 2019,123 patients with hypertrophic scars in the Dermatology Clinic,the Second Affilia-ted Hospital of Anhui Medical University.Observation group included 63 cases,30 males and 33 fe-males,aged 7 to 69(31.7±14.6)years;given lomatasone cream for topical application,once in the morning and evening,combined with lattice laser transdermal administration,once a week for 3 months.There were 60 patients in the control group,28 males and 32 females,aged 10-71(32.8±15.1)years;topical lomidasone cream was given,one morning and one evening,with a course of 3 months.Results Clnical trials were completed in 123 patients.The total effective rate in the obser-vation group was 66.7%(42/63),of which 18 cases were cured,and 18 cases were markedly effec-tive;6 cases were effective,21 cases were ineffective;the total effective rate in the control group was 20.0%(12/60),of which 0 cases were cured,and the effect was 7 Cases,and 5 cases were effective,48 cases were ineffective.The effective rate of the observation group was significantly better than that of the control group(P<0.05),and there were no adverse reactions in the observation group.Conclusions Lattice laser transdermal administration combined with halomethasone cream for topical treatment of hypertrophic scars is effective,safe,and worthy of clinical application.

关 键 词：瘢痕 肥大性 治疗结果 点阵激光 卤米松 透皮给药 

分 类 号：R622[医药卫生—整形外科]