2018年陕西省彬县大骨节病病区成人及学龄儿童发硒特征分析  

Hair selenium characteristics of adults and school-age children in Kaschin-Beck disease area in Binxian,Shaanxi,2018

作　　者：王晓亚 李海蓉[1,2] 杨林生 孔畅[1,2] 李盈春 Wang Xiaoya;Li Hairong;Yang Linsheng;Kong Chang;Li Yingchun(Key Laboratory of Land Surface Pattern and Simulation,Institute of Geographical Sciences and Natural Resources Research,Chinese Academy of Sciences,Beijing 100101,China;College of Resources and Environment,Chinese Academy of Sciences,Beijing 100190,China;Binxian Center for Disease Prevention and Control,Binxian 713500,China)

机构地区：[1]中国科学院地理科学与资源研究所“陆地表层格局与模拟”院重点实验室,北京100101 [2]中国科学院大学资源与环境学院,北京100190 [3]陕西省咸阳市彬县疾病预防控制中心,713500

出　　处：《中华地方病学杂志》2020年第2期104-107,共4页Chinese Journal of Endemiology

基　　金：国家自然科学基金(41671500)。

摘　　要：目的 了解陕西省彬县大骨节病病区成人及学龄儿童硒营养现状,为采取针对性措施提供依据。方法 2018年,依据大骨节病病情将彬县划分为5个病区等级,选择11个有代表性病区村作为调查村,每个调查村划分为东、西、南、北、中5个方位,每个方位选择2户村民,采集成人发样,进行发硒含量测定。在5个病区等级对应的乡镇小学及1个村小学,采集学龄儿童发样,进行发硒含量测定。结果 共采集成人发样85份,发硒含量均值为231.7 μg/kg,总体处于边缘硒缺乏水平(200 ~ < 250 μg/kg),不同病区等级间成人发硒含量比较差异无统计学意义(χ2 = 5.616,P > 0.05);共采集儿童发样162份,发硒含量均值为301.3 μg/kg,总体处于中等硒营养水平(250 ~ < 500 μg/kg),不同病区等级儿童发硒含量比较差异有统计学意义(χ2 = 13.627,P < 0.05)。结论 彬县虽从整体上摆脱了大骨节病风险,但是部分成人及儿童硒营养水平仍较低,需加强防控,尤其是针对生活在历史病情相对较重的病区村的学龄儿童。Objective To assess the present situation of selenium nutrition in adults and school-age children in Kaschin-Beck disease area of Binxian,Shaanxi Province,and provide the basis for taking targeted measures.Methods Binxian was divided into five grades according to the condition of Kaschin-Beck disease,and 11 representative villages were selected as the survey villages in 2018.Each survey village was located in five directions:east,west,south,north,and middle.Two household villagers were selected from each location,and adult hair samples were collected for hair selenium content determination.And school-age children hair samples were collected at the township central primary schools and 1 village primary school corresponding to the five ward levels,and the selenium content was determined.Results A total of 85 adult hair samples were collected,the average selenium content was 237.1μg/kg,generally at the marginal selenium deficiency level(200-<250μg/kg),and there was no significant difference among different grades of disease areas(χ2=5.616,P>0.05).A total of 162 children hair samples were collected,the average selenium content was 301.3μg/kg,generally at the middle selenium nutrition level(250-<500μg/kg),and there was significant difference among different grades of disease areas(χ2=13.627,P<0.05).Conclusion Although Binxian has got rid of the risk of Kaschin-Beck disease as a whole,the selenium nutrition levels of some adults and children are still low,so it is still necessary to strengthen the prevention and control measures,especially for school-age children living in a relatively serious historical disease villages.

关 键 词：硒 大骨节病 头发 儿童 成人 

分 类 号：R6[医药卫生—外科学]