一种香豆素类荧光探针的合成及其性能研究  

Synthesis and Properties of A Coumarin-based Fluorescent Probe

作　　者：孙石丽 张慧 俞天智 赵玉玲[2] Sun Shili;Zhang Hui;Yu Tianzhi;Zhao Yuling(Key Laboratory of Opto-Electronic Technology and Intelligent Control(Ministry of Education),Lanzhou Jiaotong University,Lanzhou,730070;School of Chemical and Biological Engineering,Lanzhou Jiaotong University,Lanzhou,730070)

机构地区：[1]兰州交通大学光电技术与智能控制教育部重点实验室,兰州730070 [2]兰州交通大学化学与生物工程学院,兰州730070

出　　处：《化学通报》2020年第5期448-452,共5页Chemistry

基　　金：国家自然科学基金项目(51563014);甘肃省自然科学基金项目(1606RJZA018)资助。

摘　　要：本文设计合成了一种基于香豆素的荧光探针L,通过氢谱、质谱对其结构进行表征。该探针在DMSO/H2O(体积比9∶1)体系中对Co^2+和Ni^2+具有较好的选择性和灵敏度。Co^2+和Ni^2+的加入使得探针L的荧光发射发生猝灭,其他金属离子未对探针的荧光产生明显的影响。探针L与Co^2+和Ni^2+的配位比均为1∶2,其对Co2+和Ni^2+的检出限分别为1.002×10^-7和9.78×10^-6 mol/L,结合常数分别是1.06×10^6和9.84×10^5 L·mol^-1。A coumarin-based fluorescent probe L was synthesized. Its structure was characterized by NMR and MS. The probe has high selectivity and sensitivity towards Co^2+ and Ni^2+ in DMSO/water(v/v=9∶1) solvent. Upon the addition of Co^2+ or Ni^2+, the probe L displayed remarkable fluorescence quenching, which could not be interfered by other metal ions. The results showed that the coordination ratio of probe L to Co^2+ and Ni^2+ is 1∶2. The detection limits for Co^2+ and for Ni^2+ are 1.002×10^-7mol/L and 9.78×10^-6mol/L, and the binding constants are 1.06×10^6 L·mol^-1 and 9.84×10^5L·mol^-1, respectively.

关 键 词：香豆素 荧光探针 荧光猝灭 CO^2+ NI^2+ 

分 类 号：O657.3[理学—分析化学] X85[理学—化学]