罗阿丝虫病  

A case report of loiasis

作　　者：元慧杰[1] 王剑飚[2] 璩斌[2] 陈家旭[3] 郑捷[1] 潘萌[1] YUAN Hui-jie;WANG Jian-biao;QU Bin;CHEN Jia-xu;ZHENG Jie;PAN Meng(Department of Dermatology,Rui Jin Hospital,School of Medicine,Shanghai Jiao Tong Universily,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院皮肤科,上海200025 [2]上海交通大学医学院附属瑞金医院检验科,上海200025 [3]中国疾病预防控制中心寄生虫病预防控制所,上海200025

出　　处：《临床皮肤科杂志》2020年第5期278-280,共3页Journal of Clinical Dermatology

基　　金：国家自然科学基金重点项目(81730085);国家自然科学基金青年项目(81803128);上海市青年科技英才扬帆计划(18YF1414200)。

摘　　要：报告1例罗阿丝虫病误诊为嗜酸性筋膜炎。患者男,45岁。因双上肢皮肤肿胀伴嗜酸性粒细胞升高2年余就诊,外院行肌肉活检及组织病理检查,诊断为嗜酸性筋膜炎。口服甲泼尼龙治疗后外周血嗜酸性粒细胞计数下降,但糖皮质激素减量后血嗜酸性粒细胞计数再次升高。患者入我科后,外周血及骨髓中镜检发现罗阿丝虫微丝蚴,确诊为罗阿丝虫病并予伊维菌素治疗,患者症状缓解,复查外周血微丝蚴数量明显减少,嗜酸性粒细胞计数显著下降。A case of loiasis misdiagnosed as eosinophilic fasciitis was reported. A 45-year-old male with skin swelling on his bilateral upper limbs and elevated peripheral eosinophil(EOS) counts for 2 years was admitted to our hospital. He was misdiagnosed as eosinophilic fasciitis after muscle histopathological examination in another hospital. After oral methylprednisolone treatment, his peripheral EOS counts decreased initially but then increased again with the reduction of glucocorticoid dosage. After admission to our hospital, since Loa loa microfilariae were found in his peripheral blood and bone marrow, he was diagnosed with loiasis. The patient was then treated with ivermectin, which relieved his swelling and dramatically reduced his peripheral microfilariae count and EOS.

关 键 词：罗阿丝虫病 误诊 

分 类 号：R757.9[医药卫生—皮肤病学与性病学]