DABCO类离子液体的合成及其在Baylis-Hillman反应中的应用  

Synthesis of DABCO-Based Ionic Liquids and Their Application in Baylis-Hillman Reaction

作　　者：汪晨光 冯菊红 张恒宜 罗文涛 王喻华 胡学雷 WANG Chenguang;FENG Juhong;ZHANG Hengyi;LUO Wentao;WANG Yuhua;HU Xuelei(Key Laboratory of Green Chemical Process of Ministry of Education,School of Chemical Engineering and Pharmacy,Wuhan Institute of Technology,Wuhan 430074,China)

机构地区：[1]武汉工程大学化工与制药学院,绿色化工过程教育部重点实验室,湖北武汉430074

出　　处：《化学与生物工程》2020年第5期6-10,共5页Chemistry & Bioengineering

基　　金：湖北省自然科学基金重点项目(2011CDA048)。

摘　　要：以三乙烯二胺、溴代烷烃、四氟硼酸钠为原料初步合成了4种DABCO类离子液体,并将其用于催化芳香醛类与丙烯酸酯类的Baylis-Hillman反应,考察了DABCO类离子液体在Baylis-Hillman反应中的催化性能,讨论了反应溶剂、催化剂的烷基链链长、催化剂用量(摩尔分数,以芳香醛计)对反应速率及收率的影响,并对DABCO类离子液体进行回收利用实验。结果表明,在室温条件下,DABCO类离子液体在Baylis-Hillman反应中表现出了良好的催化效果,有效促进了反应的进行,缩短了反应时间;当催化剂[C4dabco][BF4]用量为80%、以水为溶剂时,7.0 h完成反应,收率为89.1%,回收后的催化剂循环使用6次仍能保持良好的催化活性。Using triethylene diamine,bromoalkane,and sodium tetrafluoroborate as raw materials,we preliminarily synthesized four kinds of DABCO-based ionic liquids,which were used as catalysts in Baylis-Hillman reaction of aromatic aldehydes and acrylates.Moreover,we investigated the catalytic performance of DABCO-based ionic liquids in Baylis-Hillman reaction,and discussed the effects of reaction solvent,length of alkyl chain of catalyst,and catalyst amount(molar fraction,based on aromatic aldehyde)on the reaction rate and yield.Furthermore,we conducted the recycling experiment of DABCO-based ionic liquids.The results show that,at room temperature,DABCO-based ionic liquids have good catalytic effects in Baylis-Hillman reaction,effectively promote the reaction and shorten the reaction time.The yield will be 89.1%when the catalyst[C4dabco][BF4]amount is 80%,water is used as the solvent,and the reaction time is 7.0 h.The recovered catalyst can still maintain good catalytic activity after recycling 6 times.

关 键 词：DABCO类离子液体 BAYLIS-HILLMAN反应 催化性能 循环使用 

分 类 号：O621.3[理学—有机化学]