用二甲双胍联合克罗米芬治疗多囊卵巢综合征的效果分析  

Effect analysis of metformin combined with clomiphene in the treatment of polycystic ovary syndrome

作　　者：杨丽 Yang Li(the first people’s hospital of jining,Jining Shandong 272100)

机构地区：[1]济宁第一人民医院,山东济宁272100

出　　处：《当代医药论丛》2020年第7期11-12,共2页

摘　　要：目的:探讨用二甲双胍联合克罗米芬治疗多囊卵巢综合征的效果.方法:选取济宁第一人民医院收治的60例多囊卵巢综合征患者作为本次研究的对象.将这些患者平均分为对照组和观察组.在两组患者入院后,为对照组患者使用克罗米芬进行治疗,为观察组患者联用二甲双胍和克罗米芬进行治疗.然后比较两组患者治疗的效果.结果:治疗后,观察组患者卵泡的发育率高于对照组患者,P<0.05;其空腹胰岛素、血清睾酮的水平及卵泡刺激素/黄体生成素值均低于对照组患者,P<0.05.结论:用二甲双胍联合克罗米芬治疗多囊卵巢综合征的效果较为理想,可有效地促进该病患者卵泡的发育.Objective:To investigate the effect of metformin combined with clomiphene in the treatment of polycystic ovary syndrome(pcos).Methods:60 patients with polycystic ovary syndrome admitted to jining first people’s hospital were selected as the subjects of this study.The patients were divided equally into control and observation groups.After admission,the control group was treated with clomiphene,and the observation group was treated with metformin and clomiphene.The results were then compared between the two groups.Results:after treatment,the follicular development rate of the observation group was higher than that of the control group,P<0.05.The levels of fasting insulin,serum testosterone and FSH/luteinizing hormone were all lower than those of the control group,P<0.05.Conclusion:the effect of metformin combined with clomiphene in the treatment of polycystic ovary syndrome(pcos)is ideal,which can effectively promote the development of follicles in pcos patients.

关 键 词：二甲双胍 克罗米芬 多囊卵巢综合征 促卵泡发育 

分 类 号：R711[医药卫生—妇产科学]