The circulation of unique reassortment strains of infectious bursal disease virus in Pakistan  

作　　者：Altaf HUSSAIN WU Tian-tian FAN Lin-jin WANG Yu-long Farooq Khalid MUHAMMAD JIANG Nan GAO Li LI Kai GAO Yu-long LIU Chang-jun CUI Hong-yu PAN Qing ZHANG Yan-ping Asim ASLAM Khan MUTI-UR-REHMAN Muhammad Imran ARSHAD Hafiz Muhammad ABDULLAH WANG Xiao-mei QI Xiao-le 

机构地区：[1]Division of Avian Infectious Diseases,State Key Laboratory of Veterinary Biotechnology,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150069,P.R.China [2]OIE Reference Laboratory for Infectious Bursal Disease,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150069,P.R.China [3]Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Disease and Zoonoses,Yangzhou 225009,P.R.China [4]Sub-campus Toba Tek Singh,University of Agriculture Faisalabad,Faisalabad 38040,Pakistan [5]Pathology Department,University of Veterinary and Animal Sciences,Lahore 54660,Pakistan [6]Institute of Microbiology,University of Agriculture Faisalabad,Faisalabad 38040,Pakistan [7]Department of Animal Sciences,Ohio State University,Columbus 43210,USA1

出　　处：《Journal of Integrative Agriculture》2020年第7期1867-1875,共9页农业科学学报（英文版）

基　　金：This work was supported by the National Key Research and Development Program of China(2016YFE0203200,2017YFD0500704);the Heilongjiang Province Foundation for the National Key Research and Development Program of China(GX18B011);the National Natural Science Foundation of China(31430087);the earmarked fund for the China Agriculture Research System(CARS-41-G15).

摘　　要：Infectious bursal disease(IBD),caused by IBD virus(IBDV),is one of the most devastating and immunosuppressive diseases of the poultry and has been a constraint on the sustainable poultry production around the globe including Pakistan.While the disease is threatening the poulty industry,the nature of predominant strains of IBDV in Pakistan remained l-defined.In this study,an epidemiology survey was conducted in the main chicken-farming regions of Pakistan.The batch of Pakistan IBDVs genes simultaneously covering both VP1 and VP2 were amplified,sequenced,and analyzed.The unique segment-reassortant IBDVs(vv-A/Uniq-B),carrying segmentA from vvIBDV and segment B from one unique ancestor,were identifed as one important type of circulating strains in Pakistan.The data also discovered the characteristic molecular features of Pakistan IBDVs,which will contribute to scientific vaccine selection and effective prevention of the disease.

关 键 词：infectious bursal disease virus circulating strains REASSORTANT Pakistan 

分 类 号：S855[农业科学—临床兽医学]