Defecation function and quality of life in patients with slow-transit constipation after colectomy  

作　　者：Yue Tian Li Wang Jing-Wang Ye Yong Zhang Hui-Chao Zheng Hao-De Shen Fan Li Bao-Hua Liu Wei-Dong Tong 

机构地区：[1]Department of General Surgery,Daping Hospital,Army Medical University,Chongqing 400042,China

出　　处：《World Journal of Clinical Cases》2020年第10期1897-1907,共11页世界临床病例杂志

基　　金：Supported by the National Natural Science Foundation of China,No.81270461,No.81570483 and No.81770541.

摘　　要：BACKGROUND Although total or subtotal colectomy for slow-transit constipation(STC)has been proven to be a definite treatment,the associated defecation function and quality of life(QOL)are rarely studied.AIM To evaluate the effectiveness of surgery for STC regarding defecation function and QOL.METHODS From March 2013 to September 2017,30 patients undergoing surgery for STC in our department were analyzed.Preoperative,intra-operative,and postoperative 3-mo,6-mo,1-year,and 2-year follow-up details were recorded.Defecation function was assessed by bowel movements,abdominal pain,bloating,straining,laxative,enema use,diarrhea,and the Wexner constipation and incontinence scales.QOL was evaluated using the gastrointestinal QOL index and the 36-item short form survey.RESULTS The majority of patients(93.1%,27/29)stated that they benefited from the operation at the 2-year follow-up.At each time point of the follow-up,the number of bowel movements per week significantly increased compared with that of the preoperative conditions(P<0.05).Similarly,compared with the preoperative values,a marked decline was observed in bloating,straining,laxative,and enema use at each time point of the follow-up(P<0.05).Postoperative diarrhea could be controlled effectively and notably improved at the 2-year follow-up.The Wexner incontinence scores at 6-mo,1-year,and 2-year were notably lower than those at the 3-mo follow-up(P<0.05).Compared with those of the preoperative findings,the Wexner constipation scores significantly decreased following surgery(P<0.05).Thus,it was reasonable to find that the gastrointestinal QOL index scores clearly increase(P<0.05)and that the 36-item short form survey results displayed considerable improvements in six spheres(role physical,role emotional,physical pain,vitality,mental health,and general health)following surgery.CONCLUSION Total or subtotal colectomy for STC is not only effective in alleviating constipation-related symptoms but also in enhancing patients’QOL.

关 键 词：Slow-transit constipation COLECTOMY Defecation function Wexner constipation and incontinence scales Quality of life Gastrointestinal quality of life index 

分 类 号：R656.9[医药卫生—外科学]