选择性阻断肝动脉在肝囊型包虫外囊完整剥离术中的应用分析  

Application analysis of selective blocking of hepatic artery blood in external capsule excision for hepatic cystic echinococosis

作　　者：杨学安 张新峰[1] 邵英梅[1] 吐尔干艾力·阿吉[1] 尼加提·塔西甫拉提 王飞 徐克 阿依甫汗·阿汗[1] Yang Xuean;Zhang Xinfeng;Shao Yingmei;Tuerganaili Aji;Nijiati Taxifulati;Wang Fei;Xu Ke;Ayifuhan Ahan(Department of Hepatobiliary Hydatid Diseases,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China)

机构地区：[1]新疆医科大学第一附属医院肝胆包虫外科,乌鲁木齐830011

出　　处：《中华肝胆外科杂志》2020年第5期345-348,共4页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的探讨选择性阻断肝动脉血流在肝囊型包虫外囊完整剥离术中的应用效果。方法回顾分析新疆医科大学第一附属医院2017年1月至2019年1月连续接受手术治疗的80例肝囊型包虫病患者资料,其中男性36例,女性44例,平均年龄47岁。所有患者均行肝包虫外囊完整剥离术,依据术中血流阻断不同分为:A组(n=42),选择性阻断肝动脉;B组(n=38),阻断第一肝门血流。比较两组住院天数、术中出血量、术后通气时间以及并发症。比较两组术后丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、白蛋白、总胆红素。结果A组术中出血量(215.7±29.6)ml、术后通气时间(2.3±0.1)d、住院天数(11.6±1.0)d,少于B组(254.8±20.6)ml、(3.2±0.2)d、(12.7±0.7)d,差异有统计学意义(均P<0.05)。A组术后发生并发症4例(9.5%),B组发生并发症5例(13.2%),两组比较差异无统计学意义(P>0.05)。A组术后第3天ALT、AST、白蛋白和总胆红素均优于B组,差异有统计学意义(均P<0.05)。A组术后第5天ALT(62.8±5.2)U/L、AST(32.7±2.6)U/L、白蛋白(39.1±0.3)g/L、总胆红素(12.1±0.5)μmol/L,均优于B组(121.9±5.6)U/L、(53.9±8.0)U/L、(32.2±0.6)g/L、(19.3±0.9)μmol/L,差异有统计学意义(均P<0.05)。结论肝囊型包虫病外囊完整剥离术中选择性阻断肝动脉,在控制术中出血以及术后肝功能恢复等方面优于传统第一肝门血流阻断法。Objective To study the impact of selective occlusion of hepatic arterial blood flow in external capsule excision for hepatic cystic echinococcosis.Methods A retrospective analysis was conducted on the data of 80 patients with hepatic cystic echinococcosis who underwent surgical treatment from January 2017 to January 2019 in the First Affiliated Hospital of Xinjiang Medical University. There were 36 males and 44 females, with an average age of 47 years. All patients underwent external capsule excision of hepatic cystic echinococcosis. According to the type of intraoperative blood flow occlusion, the patients were divided into: group A (n=42), selective occlusion of hepatic artery;group B (n=38), Pringle’s maneuvre. The hospitalization stay, intraoperative blood loss, postoperative ventilation time and complications were compared between the two groups. The postoperative alanine aminotransferase (ALT), aspartate aminotransferase (AST), albumin, and total bilirubin were compared between the two groups.Results The intraoperative blood loss (215.7±29.6) ml, postoperative ventilation time (2.3±0.1)d, and hospital stay (11.6±1.0) d in group A were better than those in group B (254.8±20.6) ml, (3.2±0.2) d, (12.7±0.7) d, the differences were significant (all P<0.05). There were 4 patients (9.5%) who developed postoperative complications in group A and 5 patients (13.2%) in group B. There was no significant difference between the two groups (P>0.05). Group A had better ALT, AST, albumin, and total bilirubin on day 3 after operation, and the differences were significant (all P<0.05). The ALT (62.8±5.2) U/L, AST (32.7±2.6) U/L, albumin (39.1±0.3) g/L, total bilirubin (12.1±0.5) μmol/L in Group A were better than group B (121.9±5.6) U/L, (53.9±8.0) U/L, (32.2±0.6) g/L, (19.3±0.9) μmol/L on day 5 after operation, the differences were significant (all P<0.05).Conclusion Selective occlusion of the hepatic artery in external capsule excision for hepatic cystic echinococcosis was superior to the traditional Pring

关 键 词：棘球蚴病 肝 肝动脉 并发症 肝功能恢复 

分 类 号：R657.3[医药卫生—外科学]