纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎的效果  

Effect of Alveolar Lavage Under Fiberoptic Bronchoscope in Treatment of Ventilator-associated Pneumonia

作　　者：陈慧丽 朱锋[1] 汪漩 俞洪韵 龚佩丽[1] 瞿昌晶[1] CHEN Hui-li;ZHU Feng;WANG Xuan;YU Hong-yun;GONG Pei-li;QU Chang-jing(Department of Intensive Medicine,Central Hospital of Yangpu District,Shanghai 200090,China)

机构地区：[1]上海市杨浦区中心医院重症医学科,上海200090

出　　处：《医学信息》2020年第11期107-108,共2页Journal of Medical Information

摘　　要：目的探讨纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎的临床疗效。方法选取2017年4月~2019年8月我院收治的呼吸机相关性肺炎患者102例作为研究对象,采用随机数字表法分为对照组和观察组,每组51例。对照组行常规治疗,观察组在对照组基础上行纤维支气管镜下肺泡灌洗辅助治疗,比较两组治疗效果、炎性因子水平[C-反应蛋白(CRP)、白介素-8(IL-8)]。结果观察组治疗总有效率为96.08%,高于对照组的82.35%,差异有统计学意义(P<0.05);治疗后,两组CRP、IL-8水平均较治疗前降低,且观察组低于对照组,差异有统计学意义(P<0.05)。结论经纤维支气管镜下肺泡灌洗辅助治疗呼吸机相关性肺炎临床效果确切,可有效降低患者炎性因子水平,改善炎性反应,促进患者病情恢复。Objective To explore the clinical efficacy of fiberoptic bronchoscopic alveolar lavage in the adjuvant treatment of ventilator-associated pneumonia.Methods A total of 102 patients with ventilator-associated pneumonia admitted in our hospital from April 2017 to August 2019 were selected as the research object,using the random number table method to divided into control group and observation group,with 51 cases in each group.The control group received routine treatment,and the observation group underwent adjuvant alveolar lavage under the control of the bronchofibroscope,compare the treatment effect and inflammatory factor level[C-reactive protein(CRP),interleukin-8(IL-8)]changes between the two groups.Results The total effective rate of treatment in the observation group was 96.08%,higher than 82.35%that in the control group,the difference was statistically significant(P<0.05);After treatment,the levels of CRP and IL-8 in the two groups were lower than before treatment,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).Conclusion The alveolar lavage under fiberoptic bronchoscopy has a definite clinical effect on the treatment of ventilator-associated pneumonia.It can effectively reduce the level of inflammatory factors,improve the inflammatory response,and promote the recovery of the patient's condition.

关 键 词：纤维支气管镜 肺泡灌洗 呼吸机相关性肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]