急性冠脉综合征患者经皮冠状动脉介入治疗后非罪犯血管病变进展危险因素及防治策略的研究进展  

Research Progress on Risk Factors of Progression and Control Strategy of Non-culprit Coronary Lesions in Post-PCI Patients with Acute Coronary Syndrome

作　　者：姚冰琪 黄淑田[1] 葛婕丽 台鸣娟 台润东 YAO Bingqi;HUANG Shutian;GE Jieli;TAI Mingjuan;TAI Rundong(Department of Cardiovascular Medicine,the Second Hospital of Shanxi Medical University,Taiyuan 030000,China)

机构地区：[1]山西医科大学第二医院心血管内科,山西省太原市030000

出　　处：《实用心脑肺血管病杂志》2020年第6期94-99,共6页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：45%以上的急性冠脉综合征(ACS)患者伴有多支血管病变(MVD),而非罪犯血管病变(NCCLs)进展与ACS伴MVD患者预后密切相关,减少NCCLs相关主要不良心血管事件(MACE)已成为改善ACS伴MVD患者预后的关键,但目前ACS患者罪犯血管行经皮冠状动脉介入治疗(PCI)后是否需进一步处理NCCLs及NCCLs的最佳血运重建时机仍存在一定争议。本文对ACS患者PCI后NCCLs进展的危险因素(包括血脂异常、炎症因素、糖代谢异常、肾功能异常、阻塞性睡眠呼吸暂停低通气综合征、代谢综合征、年龄、性别、斑块特征、病变位置及类型)及防治策略进行了综述,以期为更好地改善ACS患者预后提供参考。There are more than 45%patients accompanied with multi-vessel diseases(MVD)in patients with acute coronary syndrome(ACS),however progression of non-culprit coronary lesions(NCCLs)is significantly associated with the prognosis of ACS patients complicated with MVD,reduce the risk of major adverse cardiovascular events(MACE)has become the key to improve the prognosis of such patients,but there is some controversy in necessity for intervention of NCCLs after intervention of culprit coronary lesions and the optimal opportunity for revascularization of NCCLs in patients with ACS so far.This paper reviewed the risk factors(including dyslipidemia,inflammatory factors,glucose metabolic abnormality,renal dysfunction,OSAHS,metabolic syndrome,age,gender,characteristics of plaques,locations and types of lesions)of progression and control strategy of NCCLs in post-PCI patients with ACS,in order to provide a reference for better improving the prognosis of such patients.

关 键 词：冠心病 急性冠脉综合征 血管成形术 气囊 冠状动脉 非罪犯血管病变 危险因素 综述 

分 类 号：R541.4[医药卫生—心血管疾病]