超声造影在颈动脉粥样硬化斑块评估的研究进展  

Research progress of contrast-enhanced ultrasound in the evaluation of carotid atherosclerotic plaques

作　　者：岳松[1] 刘轩[1] YUE Song;LIU Xuan(Department of Physical Examination,Tianjin Gongan Hospital,Tianjin 300042,China)

机构地区：[1]天津市公安医院物检科,天津300042

出　　处：《中国城乡企业卫生》2020年第5期79-81,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目前心脑血管疾病已成为威胁人类健康的重要疾病,被称为"人类健康的头号杀手"。颈动脉是反映全身动脉的理想窗口,颈动脉粥样硬化是全身动脉硬化的局部表现,与冠心病、脑血管疾病密切相关。国内外大量研究表明,约25%~50%的脑卒中患者与颈动脉不稳定性斑块脱落有关。斑块内新生血管形成是不稳定性斑块的重要标志之一,而传统超声检测斑块内新生血管的特异度和敏感度都较差。近年来,超声造影技术(CEUS)通过造影剂观察斑块内新生血管及其血流灌注情况对不稳定性斑块的诊断被广泛应用于临床。本文拟就CEUS及其在颈动脉粥样硬化斑块评估中的研究进展作一综述,以期为临床诊治提供帮助。At present,cardiovascular and cerebrovascular diseases have become an important disease threatening human health,known as"the number one killer of human health".Carotid artery is an ideal window to reflect the systemic artery.Carotid atherosclerosis is the local manifestation of systemic atherosclerosis,which is closely related to coronary heart disease and cerebrovascular disease.A large number of studies at home and abroad have shown that about 25%-50%of stroke patients are related to the loss of carotid artery unstable plaques.Neovascularization in plaque is one of the important signs of unstable plaques.However,the specificity and sensitivity of traditional ultrasound detection of neovascularization in plaque are poor.In recent years,contrast-enhanced ultrasound(CEUS)has been widely used in the diagnosis of unstable plaques by observing the neovascularization and blood perfusion in plaque.In this paper,CEUS and its research progress in the evaluation of carotid atherosclerotic plaques are reviewed in order to provide help for clinical diagnosis and treatment.

关 键 词：超声造影 颈动脉粥样硬化 不稳定性斑块 

分 类 号：R445[医药卫生—影像医学与核医学]