西吡氯铵含漱液联合莫沙比利预防老年人医院获得性下呼吸道感染的效果  

Effect of Ciclopridium Gargle with Moxapride in Preventing Hospital-acquired Lower Respiratory Tract Infections in the Elderly

作　　者：赵亮[1] ZHAO Liang(Department of Emergency Medicine,Union Medical College Hospital,Fujian Medical University,Fuzhou,Fujian Province,350000 China)

机构地区：[1]福建医科大学附属协和医院急诊内科,福建福州350000

出　　处：《中外医疗》2020年第12期99-101,共3页China & Foreign Medical Treatment

摘　　要：目的探讨西吡氯铵含漱液联合莫沙比利预防老年人医院获得性下呼吸道感染的效果。方法在2018年6月-2019年5月时间段内,从该院接收治疗的具有发生医院获得性下呼吸道感染高危因素的老年住院患者当中随机抽取100例作为该次研究对象,按照随机原则将患者分成对照组(50例)和观察组(50例),对照组不采取措施,观察组采用西吡氯铵含漱液联合莫沙比利方案进行预防,对两组治疗效果进行比较分析,明确西吡氯铵含漱液联合莫沙比利方案应用价值。结果观察组和对照组医院获得性下呼吸道感染发生率分别为4.0%和22.0%,两组比较差异有统计学意义(χ^2=12.535,P<0.05);观察组和对照组不良反应发生率分别为10.0%和8.0%,两组比较差异无统计学意义(χ^2=0.522,P>0.05)。结论采用西吡氯铵含漱液联合莫沙比利方案来预防老年人医院获得性下呼吸道感染,效果显著,可以有效降低医院获得性下呼吸道感染的发生率,并且不会对患者造成严重的不良反应,值得临床推广和应用。Objective To explore the effect of cetylpyridine gargle combined with moxapride in preventing hospital-acquired lower respiratory tract infections in the elderly.Methods During the period from June 2018 to May 2019,100 elderly patients with high risk factors for hospital-acquired lower respiratory tract infection who received treatment from our hospital were randomly selected as the research object according to the random principle.The patients were divided into a control group(50 cases)and an observation group(50 cases).The control group did not take any measures.The observation group was treated with cetylpyridinium gargle combined with the moxapride regimen for prevention.The treatment effects of the two groups were compared and analyzed,to clarify the application value of cetyl ammonium gargle combined with mosapride.Results The incidences of hospital-acquired lower respiratory tract infections in the observation group and the control group were 4.0%and 22.0%,respectively.The differences between the two groups were significant(χ^2=12.535,P<0.05);the incidences of adverse reactions in the observation group and the control group were 10.0%and 8.0%,there was no significant difference between the two groups(χ^2=0.522,P>0.05).Conclusion The use of cetyl ammonium gargle combined with the mosapride regimen to prevent hospital-acquired lower respiratory tract infections in the elderly has a significant effect,can effectively reduce the incidence of hospital-acquired lower respiratory tract infections,and will not cause serious illness to patients.The adverse reaction are worth clinical promotion and application.

关 键 词：医院获得性下呼吸道感染 西吡氯铵含漱液 合莫沙比利 效果 

分 类 号：R656[医药卫生—外科学]