广州市部分职业人群肺小气道功能异常影响因素分析  

Influencing factors of pulmonary small airway dysfunction in some occupational populations in Guangzhou City

作　　者：周浩[1,2] 丘丛玺 林秋月[1,2] 刘鑫 李艳华[1,2] 肖吕武 刘移民[1,2] ZHOU Hao;QIU Congxi;LIN Qiuyue;LIU Xing;LI Yanhua;XIAO Lüwu;LIU Yimin(Occupational Health Monitoring Center,Guangzhou Occupational Disease Prevention and Treatment Center,Guangzhou,Guangdong 510620,China)

机构地区：[1]广州市职业病防治院职业健康监护中心,广东广州510620 [2]广州医科大学职业与环境卫生研究所,广东广州510620

出　　处：《中国职业医学》2020年第1期81-85,共5页China Occupational Medicine

基　　金：广东省“十二五”医学重点专科(粤卫函〔2012〕20号);广州市医药卫生科技项目(20171A011270);广州市医学重点学科建设项目(穗卫科教〔2016〕27号);广州市“121人才梯队工程”后备人才项目(穗人社发〔2011〕167号)。

摘　　要：目的了解小气道功能异常在职业人群中的检出情况及其影响因素。方法采用方便抽样方法,选择2018年进行肺通气功能检查的15490名职业健康检查者为研究对象。收集其肺通气功能检查、胸部数字化X射线摄影(DR)等结果进行分析。结果研究对象中,检出肺通气功能异常2083人,异常检出率为13.4%;检出小气道功能异常3089人,异常检出率为19.9%。二分类Logistic回归分析结果显示,女性、工作中接触有机粉尘、工作中接触致喘物、胸部DR异常、肺通气功能异常均是研究对象小气道功能异常的危险因素(P<0.05)。结论职业人群小气道功能异常与性别、职业接触致喘物等多种因素有关;针对职业人群开展小气道功能筛查或可有助于该人群呼吸系统疾病防治的前移。Objective To explore the detection of small airway dysfunction in occupational populations and its influencing factors.Methods A convenient sampling method was adopted,and 15490 occupational health workers who were tested for pulmonary ventilation function in 2018 were selected as study subjects.The results of pulmonary ventilation function examination and chest direct digital radiography(DR)were collected and analyzed.Results Among the study subjects,2083 were detected to have abnormal pulmonary ventilation function,the abnormal detection rate was 13.4%;3089 subjects were detected to have small airway dysfunction,and the abnormal detection rate was 19.9%.The two-class logistic regression analysis results suggested that female,exposure to organic dusts during work,exposure to asthmogenic during work,chest DR abnormalities and abnormal pulmonary ventilation function were risk factors for abnormal small airway function(P<0.05).Conclusion The abnormal small airway function in occupational populations is related to various factors such as gender and occupational exposure to allergens.The screening of small airway function in this group may help advance the prevention and treatment of respiratory diseases.

关 键 词：职业人群 肺功能 肺通气功能 小气道功能 影响因素 

分 类 号：R135[医药卫生—劳动卫生]