超声造影与常规超声引导下肺周围型病变穿刺对比分析  

Comparative Study on Biopsy of Peripheral Pulmonary Lesions by Contrast-enhanced Ultrasound and Conventional Vltrasound-guided

作　　者：唐敏[1] 宋建琼[1] 郑小雪[1] 魏国李 唐燕[1] 代佳霓 苟娟 Tang Min;Song Jianqiong;Zheng Xiaoxue;Wei Guoli;Tang Yan;Dai Jia'ni;Gou Juan(Department of Funetion,Center Hospital of Dazhou,Dazhou,Sichuan 635000,China)

机构地区：[1]达州市中心医院住院部功能科,四川省达州市635000

出　　处：《中国超声医学杂志》2020年第5期404-408,共5页Chinese Journal of Ultrasound in Medicine

基　　金：达州市2016年市级医学科研立项课题(No.201603)。

摘　　要：目的对比分析超声造影(CEUS)、常规超声在引导下肺周围型病变穿刺活检中的应用价值,以提高穿刺取材成功率。方法选取248例肺周围型病变患者,随机分成CEUS和常规超声引导下穿刺活检两组,将穿刺活检病理结果与纤维支气管镜检查、手术后病理检查及其他检查结果进行对比,比较两组取材成功率及并发症发生情况,同时比较CEUS引导下富血供及乏血供肺周围型病变穿刺取材情况。结果 CEUS引导下肺周围型病变穿刺活检成功率为91.60%(109/119),高于常规超声引导组(83.72%,108/129),但差异无统计学意义(P>0.05)。CEUS引导组穿刺并发症发生率为0.84%(1/119),低于常规超声引导组(5.42%,7/129),差异有统计学意义(P<0.05)。CEUS引导下富血供、乏血供肺周围型病变穿刺取材成功率分别为90%(9/10)、91.74%(100/109),差异无统计学意义(P>0.05)。完全灌注型富血供肺周围型病变穿刺取材成功率为87.50%(49/56),低于灌注缺损型富血供肺周围型病变(93.23%,51/53),但差异无统计学意义(P>0.05)。结论 CEUS引导下肺周围型病变穿刺活检并发症发生率低于常规超声引导,同时灌注缺损型富血供病变穿刺活检取材成功率略高于完全灌注型,因此CEUS在指导肺周围型病变穿刺活检中具有一定的应用价值。Objective To analyze the application value of Contrast-enhanced Ultrasound(CEUS)and conventional ultrasound in the guiding biopsy of peripheral pulmonary lesions and to improve the success rate of puncture sampling. Methods 248 patients with peripheral pulmonary lesions were randomly divided into CEUS-guided group and conventional ultrasound-guided group. The pathological results were compared with fibrobronchoscopy, postoperative pathology and other examinations. The success rate and the complications of the two groups were compared. The results of biopsy of pulmonary peripheral under the CEUS-guided was compared between abundant blood supply and poor blood supplyperipheral pulmonary elesions. Results The success rate of biopsy in CEUS-guided group was 91.60%(109/119), higher than conventional ultrasound-guided group(83.72%,108/129), but the difference was no statistically significant(P>0.05).The incidence of puncture complications in CEUS-guided group was 0.84%(1/119), lower than conventional ultrasound-guided group(5.42%, 7/129), the difference was statistically significant(P<0.05). The success rate of biopsy in abundant blood supply and poor supply peripheral pulmonary lesions was 90%(9/10) and 91.74%(100/109) respectively.There was no significant difference(P>0.05) between them. The success rate of abundant blood supply peripheral pulmonary lesions with complete perfusion was 87.50%(49/56), lower than the lesions with perfusion defect(93.23%, 51/53), but the difference was no statistically significant(P>0.05). Conclusions The incidence of complications of CEUS-guided biopsy group in peripheral pulmonary lesions is lower than conventional ultrasound-guided biopsy group,and the success rate of puncture biopsy in the perfusion defect type of abundant blood supply disease is slightly higher than that in the complete perfusion type, so CEUS has a certain application value in guiding the puncture biopsy of the peripheral pulmonary disease.

关 键 词：超声造影 常规超声 周围型肺病变 活检 

分 类 号：R445.1[医药卫生—影像医学与核医学] R563[医药卫生—诊断学]