新型冠状病毒肺炎患儿病例的临床药学监护与解读  

Clinical Pharmaceutical Care and Interpretation of Children with COVID-19

作　　者：尚飞能 黄怡蝶[1] 卢金淼[1] 朱逸清[1] 朱琳[1] 李智平[1] 徐虹 SHANG Fei-neng;HUANG Yi-die;LU Jin-miao;ZHU Yi-qing;ZHU Lin;LI Zhi-ping;XU Hong(Department of Pharmacy,National Children's Medical Center,Children's Hospital of Fudan University,Shanghai 201102,China;Department of Nephrology,National Children's Medical Center,Children's Hospital of Fudan University,Shanghai 201102,China;Department of Pharmacy,Dehong People's Hospital,Dehong 678400,China)

机构地区：[1]国家儿童医学中心,复旦大学附属儿科医院临床药学部,上海201102 [2]国家儿童医学中心,复旦大学附属儿科医院肾内科,上海201102 [3]德宏州人民医院药剂科,云南德宏678400

出　　处：《中国药学杂志》2020年第10期773-776,共4页Chinese Pharmaceutical Journal

基　　金：上海市优秀学术/技术带头人计划项目资助(19XD1400900);上海市科学技术委员会科研计划项目资助(18DZ1910604);上海市卫生计生系统重要薄弱学科建设项目资助(2016ZB0305)。

摘　　要：目的探讨儿童专科临床药师对新型冠状病毒肺炎患儿的药物治疗及开展药学监护的方法。方法通过参与我院首例儿童新型冠状病毒肺炎治疗儿童用药方案制定、药物重整、合理用药指导、分析用药过程中可能出现的药物相互作用和不良反应。结果患儿先后予清热利湿、祛邪扶正类中成药口服,雾化吸入干扰素抗病毒,经过治疗呼吸道标本核酸转为阴性,患儿治愈出院,预后良好。结论临床药师以药学服务为切入点,参与儿童新型冠状病毒肺炎的防治与药学监护,对保障儿童用药的有效性、合理性及安全性提供帮助,提高用药依从性。OBJECTIVE To investigate the methods of pharmaceutical treatment and care of COVID-19 in child by clinical pharmacist.METHODS Clinical pharmacist was involved in the treatment of the first case of COVID-19 in child in our hospital and provided the full range of clinical pharmacy services,assisting phyicians to optimize the medication regimen,on the basis of the patient's condition and laboratory results,combined with clinical practice.Potential drug interactions and adverse reactions were analyzed during treatment through drug recombination and monitor the efficacy of therapy.RESULTS The child was treated with traditional Chinese medicine by orally,inhaled atomized interferon antivira and was RT-PCR negative for SARS-CoV-2 after treatment.CONCLUSION Clinical pharmacists should use pharmaceutical care as an entry point to participate in the prevention and treatment of COVID-19.The drug monitoring service will conductive to improving the effectiveness,rationality,and safety of children's medication while improving medication compliance.

关 键 词：新型冠状病毒肺炎 儿童 临床药师 药学监护 合理用药 

分 类 号：R969.3[医药卫生—药理学] H511[医药卫生—药学]