中东呼吸综合征  

Middle East respiratory syndrome

作　　者：王晓欢[1] 严延生[1] 张智芳[1] 梁小洁 林志龙[1] WANG Xiao-huan;YAN Yan-sheng;ZHANG Zhi-fang;LIANG Xiao-jie;LIN Zhi-long(Fujian Center for Disease Control and Prevention,Priority Laboratory for Zoonoses Research of Fujian,Fuzhou 350001,China)

机构地区：[1]福建省疾病预防控制中心,福建省人兽共患病研究重点实验室,福州350001

出　　处：《中国人兽共患病学报》2020年第6期496-502,共7页Chinese Journal of Zoonoses

基　　金：福建省社会发展项目(No.2010Y0010);国家高技术研究发展计划(863计划)(No.2011AA02A114)联合资助。

摘　　要：中东呼吸综合征是2012年在沙特阿拉伯发现的一种冠状病毒病.由于地理关系,目前已知该病在中东多个国家存在.根据WHO报道,该病已蔓延或输入到27个国家.该病系呼吸道及密切接触传播,最大的一起输入性后引起人传人传播的疫情发生在韩国,包括沙特在内的其他绝大多数国家为散发疫情.业已证明传染源为蝙蝠,中间宿主为单峰骆驼,迄今为止人用疫苗尚未研制成功.本综述就该病的病原学、流行病学、分子病毒学、治疗、实验室诊断等进行概述,目的在于对该病的深入了解并加强防控.Middle East respiratory syndrome(MERS)is a novel coronavirus disease identified in Saudi Arabia in 2012,which is currently restricted in countries of the Middle East by geographical distribution,and has spread to 27 countries according to WHO reports.The disease is transmitted through the respiratory tract and close contact,caused the largest epidemic of human-to-human transmission from imported case in South Korea,2015,while the majority of of infections occurred in Saudi Arabia.It has been proved that the animal origin of MERS coronavirus is the bat,and dromedary camel acts as the intermediate host.So far no human vaccine has been developed successfully.This review summarizes in several respects such as etiology,molecular virology,epidemiology,treatment and laboratory diagnosis of the disease,facilitating comprehensive understanding and enhancing prevention and control measures for this emerging disease.

关 键 词：中东呼吸综合征 冠状病毒 病原学特征 流行病学特征 疾病防控 

分 类 号：R373.1[医药卫生—病原生物学]