真皮替代物在创面和瘢痕修复中的临床应用  

Application of dermal substitutes in wound and scar repair

作　　者：尹诗璐 秦泽莲[1] Yin Shilu;Qin Zelian(Department of Plastic and Reconstructive Surgery,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院成形外科,100191

出　　处：《中华皮肤科杂志》2020年第6期476-478,共3页Chinese Journal of Dermatology

基　　金：国家自然科学基金(81772090)。

摘　　要：烧伤、创伤、瘢痕及肿物切除术等造成的严重真皮缺失容易引起瘢痕畸形。真皮替代物能减少创面愈合过程中异常瘢痕的形成,同时有效降低瘢痕切除修复术后病理性瘢痕的发生。本文介绍常用真皮替代物和其在创面愈合及瘢痕切除术后修复中的临床应用。Severe dermal defects caused by burns,trauma,scars,tumor resection and so on are liable to form scar deformities.Dermal substitutes can reduce the formation of abnormal scars during wound healing,and effectively decrease the incidence of pathological scars after scar resection and repair.This review introduces some commonly used dermal substitutes and their clinical application in wound healing and skin repair after scar resection.

关 键 词：皮肤 人工 真皮 瘢痕 伤口愈合 真皮替代物 瘢痕修复 

分 类 号：R622.1[医药卫生—整形外科]