不同精子-透明质酸结合试验结合率对原因不明性不孕患者行人工授精后妊娠结局的影响  

Effect of Different Sperm-hyaluronic Acid Binding Test Combination Rate on Pregnancy Outcome after Artificial Insemination in Patients with Unexplained Infertility

作　　者：闫喜秋 YAN Xiqiu(Jiamusi Maternal and Child Health Hospital,Jiamusi 154002,China)

机构地区：[1]黑龙江省佳木斯市妇幼保健院,黑龙江佳木斯154002

出　　处：《中国医学创新》2020年第16期141-144,共4页Medical Innovation of China

摘　　要：目的:探讨不同精子-透明质酸结合试验结合率对原因不明性不孕患者行人工授精后妊娠结局的影响.方法:选择2016年1月-2018年2月于本院接受夫精人工授精的原因不明性不孕患者95例.根据精子-透明质酸结合试验结合率的不同将患者分为结合率≥65%组44例,与结合率<65%组51例.比较两组精液常规参数及妊娠结局.结果:结合率≥65%组的精液pH值、头部缺陷率、残留胞质均低于结合率<65%组,而精子浓度、前向运动百分比、活动率、正常形态率均高于结合率<65%组,差异均有统计学意义(P<0.05).结合率≥65%组的妊娠成功率为29.55%,高于结合率<65%组的11.76%,差异有统计学意义(P<0.05).两组的流产率、活产率、异位妊娠率比较,差异均无统计学意义(P>0.05).结论:精子-透明质酸结合试验能够反映精子活动力,结合率越高,原因不明性不孕患者行人工授精的妊娠成功率越高.Objective:To explore the effect of different sperm-hyaluronic acid binding test combination rate on pregnancy outcome after artificial insemination in patients with unexplained infertility.Method:A total of 95 patients with unexplained infertility who received artificial insemination from January 2016 to February 2018 in our hospital were selected.According to the different combination rate of sperm-hyaluronic acid binding test,the patients were divided into the combination rate≥65%group(44 cases)and the combination rate<65%group(51 cases).The semen routine parameters and pregnancy outcome were compared between the two groups.Result:The semen pH value,head defect rate and residual cytoplasm in the combination rate≥65%group were lower than those in the combination rate<65%group,while the sperm concentration,forward movement percentage,activity rate and normal morphology rate were higher than those in the combination rate<65%group,the differences were statistically significant(P<0.05).The pregnancy success rate of the group with combination rate≥65%group was 29.55%,higher than 11.76%of combination rate<65%group,and the difference was statistically significant(P<0.05).The abortion rate,live birth rate and ectopic pregnancy rate of the two groups were compared,the differences were not statistically significant(P>0.05).Conclusion:Sperm-hyaluronic acid binding test can reflect sperm motility.The higher the combination rate,the higher the success rate of artificial insemination in patients with unexplained infertility.

关 键 词：精子-透明质酸结合试验 原因不明性不孕 人工授精 妊娠结局 

分 类 号：R714.8[医药卫生—妇产科学]