咽喉反流与男性特发性喉接触性肉芽肿杓状软骨钙化的关系  

Relationship between laryngopharyngeal reflux and calcification of arytenoid cartilage in male patients with idiopathic laryngeal contact granuloma

作　　者：聂倩 李进让 张冉[1] 邹世桢 NIE Qian;LI Jinrang;ZHANG Ran;ZOU Shizhen(Anhui Medical University,Hefei,230031,China;Department of Otorhinolaryngology Head and Neck Surgery,the Sixth Medical Center of PLA General Hospital)

机构地区：[1]安徽医科大学,合肥230031 [2]解放军总医院第六医学中心耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2020年第3期263-265,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨咽喉反流与男性特发性喉接触性肉芽肿杓状软骨钙化的关系。方法:选择有喉部薄层CT和治疗前有咽喉反流症状指数量表(RSI)资料的92例男性特发性喉接触性肉芽肿患者的临床资料进行回顾性分析,采用SPSS 16.0软件进行Chi-square统计,分析咽喉反流与杓状软骨钙化之间的关系。结果:92例患者中,RSI>13的患者44例(47.83%),RSI≤13的患者48例(52.17%)。单侧肉芽肿87例(94.57%),双侧肉芽肿5例(5.43%)。共有病变97侧,其中杓状软骨钙化87侧(89.69%),无钙化10侧(10.31%)。RSI>13的患者中杓状软骨钙化45侧(45/46,97.83%),无钙化1侧(1/46,2.17%);RSI≤13的患者中杓状软骨钙化42侧(42/51,82.35%),无钙化9侧(9/51,17.65%)。RSI>13的患者杓状软骨钙化率高于RSI≤13者(χ~2=4.701,P=0.030)。结论:伴有咽喉反流的男性特发性喉接触性肉芽肿患者病变侧杓状软骨钙化率高于无咽喉反流者,咽喉反流可能加重或促进肉芽肿的炎症反应,加速杓状软骨的钙化。Objective: To investigate the relationship between laryngopharyngeal reflux and arytenoid cartilage calcification in male idiopathic laryngeal contact granuloma. Method: The clinical data of 92 male patients with idiopathic laryngeal contact granuloma who had the thin laryngeal CT scan images and laryngeal reflux symptom index(RSI) scale data before treatment were analyzed retrospectively. The effect of laryngopharyngeal reflux on the calcification of arytenoid cartilage in laryngeal contact granuloma patients was analyzed by Chi-square statistics with SPSS 16.0 software. Result: Among the 92 patients, 44 patients with RSI>13(47.83%) and 48 patients with RSI≤13(52.17%). Unilateral granuloma was found in 87 cases(94.57%) and bilateral granuloma in 5 cases(5.43%). A total of 97 sides of the diseased side, there were 87 sides of arytenoid cartilage with calcification(89.69%) and 10 sides without calcification(10.31%). Among the patients with RSI>13, there were 45 sides of arytenoid cartilage with calcification(45/46, 97.83%) and one side without calcification(1/46, 2.17%), and in the patients with RSI≤13, there were 42 sides of arytenoid cartilage with calcification(42/51, 82.35%) and 9 sides without calcification(9/51, 17.65%). The calcification rate of arytenoid cartilage in patients with RSI>13 group was significantly higher than that in RSI≤13 group(χ~2=4.701, P=0.030). Conclusion: The calcification rate of arytenoid cartilage in male idiopathic laryngeal contact granuloma patients with laryngopharyngeal reflux is higher than that in patients without laryngopharyngeal reflux. Laryngopharyngeal reflux may aggravate or promote the inflammatory reaction of granuloma and accelerate the calcification of arytenoid cartilage.

关 键 词：咽喉反流 喉接触性肉芽肿 杓状软骨 钙化 

分 类 号：R767[医药卫生—耳鼻咽喉科]