吲哚菁绿分子荧光影像在原发性肝癌的应用进展  

Application progress of indocyanine green fluorescence imaging in primary liver cancer

作　　者：方驰华[1] 曾思略 杨剑[1] Fang Chihua;Zeng Silue;Yang Jian(First Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangdong Provincial Clinical and Engineering Center of Digital Medicine, Guangdong Guangzhou 510282, China)

机构地区：[1]南方医科大学珠江医院肝胆一科,广东省数字医学临床工程技术研究中心,广东广州510282

出　　处：《腹部外科》2020年第3期167-170,共4页Journal of Abdominal Surgery

基　　金：“十一五”国家高技术研究发展计划(863计划)(2006AA02Z346);“十二五”国家高技术研究发展计划(863计划)(2012AA021105);“十三五”国家重点研发计划数字诊断与治疗装备研发重点专项(2016YFC0106500);国家自然科学基金重大科研仪器研制项目(81627805);国家自然科学基金-广东联合基金(U1401254);广东省自然科学基金(6200171);广东省重大科技专项(2012A080203013);广州市科技计划项目(201604020144);广东省科技计划项目(2017ZC0110);广州市产学研协同创新重大专项(201704020141)。

摘　　要：随着数字智能化技术的普及,吲哚菁绿(indocyanine green,ICG)分子荧光影像技术已得到不断的发展与完善,实现了对肝脏肿瘤的精确边界界定、微小癌灶侦测以及实时导航肝切除。ICG分子荧光影像作为一种新兴荧光成像技术,在提高手术精准性、降低手术风险、减少术后复发等方面发挥了积极作用,为肝脏肿瘤的外科诊疗提供了新的策略与手段。此文结合国内外研究现状和作者自身经验,介绍了ICG分子荧光影像在肝脏肿瘤的应用及进展。Popularization of digital intelligent technology has promoted continuous development of indocyanine green(ICG)fluorescence imaging technology,realizing precise boundary definition of liver tumors,detection of microscopic tumors,and real-time navigation resection.As an emerging fluorescence imaging technology,ICG fluorescence imaging has played an active role in improving the accuracy of surgery,reducing the risk of surgery,and reducing postoperative recurrence;it has provided new strategies and methods for the surgical diagnosis and treatment of liver tumor.Based on the research status at home and abroad as well as the author′s own experience,this paper introduces the application and progress of ICG fluorescence imaging in liver tumor.

关 键 词：吲哚菁绿 原发性肝癌 荧光成像 肝切除术 

分 类 号：R735[医药卫生—肿瘤]