全血维生素B6水平与儿童热性惊厥的相关性研究  

Study on the correlation between whole blood vitamin B6 level and febrile seizures in children

作　　者：刘素云[1] 陈思 张露娇 黄斌[1] 刘明[1] 程均[1] 易爱兰 罗勤[1] LIU Suyun;CHEN Si;ZHANG Lujiao(Department of Pediatric,Pingxiang People's Hospital,Pingxiang,Jiangxi Province,337000,China.)

机构地区：[1]江西省萍乡市人民医院儿科,萍乡337000

出　　处：《江西医药》2020年第6期653-655,共3页Jiangxi Medical Journal

基　　金：江西省卫生计生委科技计划,编号20177201。

摘　　要：目的观察全血维生素B6水平与儿童热性惊厥(febrile seizures,FS)的相关性。方法选取在我科住院的临床确诊为FS的患儿共60例为研究组,同时选取同期同年龄段因急性上呼吸道感染无惊厥病史及惊厥家族史的患儿33例为对照组。采取清晨空腹静脉血测两组患儿全血维生素B6的含量。结果研究组共60例,其中总发作次数仅1次的FS儿童31例,多次发作FS儿童29例,对照组33例,研究组与对照组儿童全血维生素B6含量比较差异无显著性(P>0.05);同样总发作次数仅1次的FS儿童全血维生素B6含量与对照组比较差异无显著性(P>0.05);但对研究组中多次发作FS儿童全血维生素B6含量与对照组进行比较,差异有显著性(P<0.05);同时对研究组中总发作次数仅1次与多次发作FS儿童全血维生素B6含量进行比较,差异亦有显著性(P<0.05)。结论多次发作FS儿童全血维生素B6含量显著降低,由此提示对于多次反复发作FS儿童可以适量补充维生素B6。Objective To observe the relevance of the whole blood vitamin B6 level and febrile seizures(FS)in children.Methods 60 children with clinical diagnosis of FS admitted to our department were selected as the study group and 33 children without history of convulsion or family history of convulsion due to acute upper respiratory tract infection at the same age were selected as the control group.Fasting venous blood in the morning was used to measure the content of whole blood vitamin B6 in the two groups.Results There were 60 cases in the study group,among which 31 children had only one attack of FS and 29 children had multiple attacks of FS,and 33 cases in the control group.There was no significant difference in the whole blood vitamin B6 content between the study group and the control group(P>0.05).Also there was no significant difference in whole blood vitamin B6 content between children who had only one attack of FS and the control group(P>0.05).However,there was significant difference in whole blood vitamin B6 content among children with multiple episodes of FS and the control group(P<0.05).At the same time,the whole blood vitamin B6 content of FS children with only one attack and multiple attacks in the study group was compared,and the difference was also significant(P<0.05).Conclusion The content of vitamin B6 in the whole blood of children with multiple FS attacks was significantly reduced,thus this study suggested that vitamin B6 could be appropriately supplemented for children with multiple FS attacks.

关 键 词：热性惊厥 维生素B6 全血 儿童 

分 类 号：R720.597[医药卫生—急诊医学]