衰弱指数对老年急性冠脉综合征患者预后预测价值分析  

Analysis of the prognostic value of frailty index in elderly patients with acute coronary syndrome

作　　者：何佳奇 齐斌 张锐 刘旭东 任平 刘娇 HE Jia-qi;QI Bin;ZHANG Rui;LIU Xu-dong;REN Ping;LIU Jiao(Department of Cardiovascular Medicine,General Hospital of North-ern Theater Command,Shenyang 110016,China)

机构地区：[1]北部战区总医院心血管内科,辽宁沈阳110016

出　　处：《临床军医杂志》2020年第5期509-510,514,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨衰弱指数对老年急性冠脉综合征患者预后的预测价值。方法回顾性分析自2016年1月至2018年12月北部战区总医院心血管内科收治的865例老年急性冠脉综合征患者的临床资料。根据Rockwood衰弱指数量表评分将患者分为衰弱组(n=489)与未衰弱组(n=376)。比较两组患者6个月内再住院、全因死亡、再发急性心肌梗死及大出血等不良事件发生率。采用多因素Logistic回归分析对衰弱指数与急性冠脉综合征预后不良事件的相关性进行分析。结果未衰弱组患者全因死亡、再住院、再发急性心肌梗死、大出血发生率均显著低于衰弱组,两组比较,差异均有统计学意义(P<0.05)。Logistic回归分析结果显示,衰弱指数是老年急性冠脉综合征患者再住院、全因死亡、再发急性心肌梗死、大出血的独立预测因素(P<0.05)。结论衰弱指数能够独立预测老年急性冠脉综合征患者再住院、全因死亡、再发急性心肌梗死及大出血等不良事件发生风险。Objective To evaluate the prognostic value of frailty index in elderly patients with acute coronary syndrome(ACS).Methods A retrospective study was performed on 865 cases of elderly patients with ACS who were admitted from January 2016 to December 2018.According to the Rockwood frailty index scale score,the patients were divided into the frailty group(n=489)and non-frailty group(n=376).The incidence rates of rehospitalization,all-cause death,recurrent acute myocardial infarction and major bleeding within 6 months were compared between the two groups.Multivariate Logistic regression analysis was used to analyze the correlation between frailty index and adverse prognostic events of acute coronary syndrome.Results The incidence of all-cause death,re-hospitalization,recurrent acute myocardial infarction and major bleeding in the non-fattening group was significantly lower than that in the fattening group,and the differences between the two groups were statistically significant(P<0.05).Logistic regression analysis showed that frailty index was an independent predictor of rehospitalization,all-cause death,recurrent acute myocardial infarction and major bleeding in elderly patients with acute coronary syndrome(P<0.05).Conclusion The frailty index independently predicted the risk of rehospitalization for acute coronary syndrome in the elderly patients with readmission,all-cause death,recurrent acute myocardial infarction and major bleeding.

关 键 词：衰弱指数 急性冠脉综合征 预后 再发急性心肌梗死 

分 类 号：R541.4[医药卫生—心血管疾病]