姜黄素对冠状动脉粥样硬化危险因素的影响  

Effects of Curcumin on Risk Factors of Coronary Atherosclerosis

作　　者：丁秀娟[1] 刘百奇[1] 王灵君[1] 孟祥龙[1] 韩健 DING Xiu-juan;LIU Bai-qi;WANG Ling-jun;MENG Xiang-long;HAN Jian(No.11 Department of Cardiology,First Hospital of Qiqihar,Qiqihar 16105,China)

机构地区：[1]黑龙江省齐齐哈尔市第一医院心内十一科,黑龙江齐齐哈尔161005

出　　处：《中国医药指南》2020年第17期39-40,共2页Guide of China Medicine

摘　　要：目的探讨姜黄素对冠状动脉粥样硬化危险因素的影响。方法随机将冠状动脉粥样硬化患者33例分为两组。接受姜黄素治疗者为实验组,接受安慰剂者为对照组。口服500毫克/粒胶囊,4次/天,持续8周。在基线和治疗后对MBI、血压、血脂、血糖和CRP等参数的变化进行统计分析。结果对照组在治疗前后参数变化无统计学意义。实验组在治疗前后相比LDL-C、VLDL、TG明显改善(P<0.05)。结论姜黄素降低了冠状动脉粥样硬化LDL-C、VLDL、TG水平,有助于预防心血管事件的发生。Objective investigate the effect of curcumin on the risk factors of coronary atherosclerosis.Methods 33 patients with coronary atherosclerosis were randomly divided into two groups.Curcumin treatment was performed in the experimental group and placebo in the control group.Oral administration of 500mg/capsule 4 times/day for 8 weeks.Changes in parameters such as MBI blood pressure,blood lipid,blood glucose and CRP were statistically analyzed at baseline and after treatment.Results In the control group,the changes of parameters before and after treatment were not statistically significant.LDL-C,VLDL,TG was significantly improved in the experimental group before and after treatment(P<0.05).Conclusions Curcumin lowers levels of ldl-c VLDL TG in coronary atherosclerosis and helps prevent cardiovascular events.

关 键 词：姜黄素 冠状动脉粥样硬化 血脂 血糖 血压 

分 类 号：R541.4[医药卫生—心血管疾病]