孟鲁司特钠治疗小儿哮喘的临床效果观察  

Observation on Clinical Effect of Treatment of Childhood Asthma by Menglusitena

作　　者：刘石[1] LIU Shi(Shenyang Fourth People's Hospital,Shenyang 110000,China)

机构地区：[1]沈阳市第四人民医院,辽宁沈阳110000

出　　处：《中国医药指南》2020年第17期143-144,共2页Guide of China Medicine

摘　　要：目的探讨孟鲁司特钠治疗小儿哮喘临床效果。方法选择我院100例2017年1月至2018年5月小儿哮喘患儿。随机分组,阿奇霉素治疗组采取阿奇霉素治疗,阿奇霉素联合孟鲁司特钠治疗组则采取阿奇霉素+孟鲁司特钠治疗。比较两组小儿哮喘控制率;咳嗽症状消失时间、哮喘症状消失时间、肺部体征消失的时间、呼吸困难消失的时间、平均住院时间;治疗前后患儿尿白三烯监测水平、血气氧分压、二氧化碳分压、免疫蛋白-E、嗜酸性粒细胞计数、C反应蛋白;药物不良反应。结果阿奇霉素联合孟鲁司特钠治疗组小儿哮喘控制率、咳嗽症状消失时间、哮喘症状消失时间、肺部体征消失的时间、呼吸困难消失的时间、平均住院时间、尿白三烯监测水平、血气氧分压、二氧化碳分压、免疫蛋白-E、嗜酸性粒细胞计数、C反应蛋白相比较阿奇霉素治疗组更好,P<0.05。阿奇霉素联合孟鲁司特钠治疗组和阿奇霉素治疗组药物不良反应相似,P>0.05。结论孟鲁司特钠治疗小儿哮喘效果确切,可有效改善患儿的病情,改善临床生化指标,促使患儿康复进程加速。Objective To explore the clinical effect of Menglusitena on childhood asthma.Methods 100 cases of children with childhood asthma from January 2017 to May 2018 were selected.Random group,azithromycin treatment group took azithromycin treatment,azithromycin combined with Menglusitena treatment group took azithromycin+Menglusitena treatment.The control rate of childhood asthma was compared between two groups.Time of loss of cough symptoms,time of disappearance of asthma symptoms,time of disappearance of lung signs,time of disappearance of dyspnea,and average hospitalization time;Before and after treatment,children with urinary leukotriene monitoring level,blood oxygen partial pressure,carbon dioxide partial pressure,immunoprotein-E,eosinophilic cell count,C reaction protein;Adverse drug reaction.Results Asthma control rate,cough symptom disappearance time,asthmatic symptom disappearance time,lung sign disappearance time,respiratory difficulty disappearance time,average hospitalization time,urinary leukotriene monitoring level,blood gas oxygen partial pressure,carbon dioxide partial pressure in the group treated with azithromycin combined with Menglusitena,immunoprotein-E,eosinophilic cell count,and C-reactive protein were better than azithromycin in the treatment group,P<0.05.Adverse drug reactions were similar in the treatment group of azithromycin combined with Menglusitena,P>0.05.Conclusion Menglusitena is effective in the treatment of childhood asthma,which can effectively improve the condition of children,improve clinical biochemical indicators,and accelerate the recovery process of children.

关 键 词：孟鲁司特钠 小儿哮喘 临床效果 

分 类 号：R725.6[医药卫生—儿科]