隔姜灸配合中药离子导入对寒凝血瘀型原发性痛经的疗效及机制研究  

Study on Curative Effect and Mechanism of Ginger-separated Moxibustion Coordinated Chinese Medicine Iontophoresis for Cold-stagnation and Blood-stasis Type Primary Dysmenorrhea

作　　者：杜美容 刘秀敏[2] 于恬 郭洁丽 代凤超 邢秀玲 DU Meirong;LIU Xiumin;YU Tian(Tangshan Municipal Maternal and Child Health Hospital,Tangshan Hebei 063000,China;Tangshan Municipal Workers'Hospital,Tangshan Hebei 063000,China)

机构地区：[1]唐山市妇幼保健院,河北唐山063000 [2]唐山市工人医院,河北唐山063000

出　　处：《四川中医》2020年第5期170-174,共5页Journal of Sichuan of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(编号:2019238)。

摘　　要：目的:观察隔姜灸配合中药离子导入治疗寒凝血瘀型原发性痛经的疗效及探讨可能机制。方法:将240例寒凝血瘀型原发性痛经患者按随机数字表法分为艾灸组、导入组和联合组各80例。在常规经期生理知识宣教基础上,艾灸组给予隔姜灸治疗,导入组给予中药离子导入治疗,联合组给予隔姜灸配合中药离子导入治疗。3组均于月经来潮前一周开始治疗,每天1次,连续7天,3个月经周期为1疗程。比较3组治疗前后的中医症状评分、血清前列腺素水平[前列腺素F2α(PGF2α)和前列腺素E2(PGE2)]和子宫动脉血流动力学参数[搏动指数(PI)和阻力指数(RI)]值,并统计3组疗效。结果:3组治疗后中医症候评分、血清PGF2α、PI和RI值均较治疗前显著降低(P均<0.05),PGE2显著升高(P<0.05);且联合组治疗后上述指标均显著优于艾灸组和导入组(P均<0.05),艾灸组和导入组上述指标比较差异均无统计学意义(P均>0.05)。联合组的治疗总有效率明显高于艾灸组和导入组(P<0.05),艾灸组和导入组治疗总有效率比较差异无统计学意义(P>0.05)。结论:隔姜灸配合中药离子导入可有效改善寒凝血瘀型原发性痛经患者的中医症候,治疗效果显著,其可能作用机制与有效调节血清前列腺素水平和改善子宫动脉血流动力学有关。Objective: To observe the curative effect and influence to serum prostate level and mechanical parameters of uterine arterial blood flow of ginger-separated moxibustion coordinated Chinese medicine iontophoresis for cold-stagnation and blood-stasis type primary dysmenorrhea.Methods: 240 cases of patients with cold-stagnation and blood-stasis type primary dysmenorrhea were randomly divided into moxibustion group,iontophoresis group and combination group,and each 80 cases.The moxibustion group received ginger-separated moxibustion on the basis of propaganda and education of menstrual physiological knowledge.And the iontophoresis group aggrandized Chinese medicine iontophoresis,while the combination group received ginger-separated moxibustion coordinated Chinese medicine iontophoresis.The three groups strated treatment one week before menstruation,once a day for seven consecutive,with 3 menstrual cycles as a course of treatment.The TCM symptom score,serum prostaglandin levels(PGF2α and PGE2) and mechanical parameters of uterine arterial blood flow(PI and RI) before and after treatment of three groups were compared.And the total effective rate of clinical treatment of the three groups were calculated.Results: The scores of TCM symptom,serum PGF2α,PI and RI of the three groups after treatment were all significantly lower than before(P<0.05),PGE2 higher(P<0.05).And those indexes in the combination group after treatment were all dramatically better than the moxibustion group and the iontophoresis group(P<0.05),while those indexes between the moxibustion group and the iontophoresis group all had no statistical significance(P>0.05).The total effective rate of clinical treatment in the combination group was obviously higher than the moxibustion group and the iontophoresis group(P<0.05),while this rate between the moxibustion group and the iontophoresis group had no statistical significance(P>0.05).Conclusion: Ginger-separated moxibustion coordinated Chinese medicine iontophoresiscan effectivly improve the TCM syndrome of

关 键 词：隔姜灸 中药离子导入 原发性痛经 寒凝血瘀 

分 类 号：R711.51[医药卫生—妇产科学]