二氢槲皮素的研究进展  

Research Progress on Dihydroquercetin

作　　者：董潞娜 曹浩 张欣宇 王海胜[1] DONG Luna;CAO Hao;ZHANG Xinyu;WANG Haisheng(Graduate School of Chinese Academy of Agricultural Sciences,Beijing 100081,China)

机构地区：[1]中国农业科学院研究生院,北京100081

出　　处：《生物技术进展》2020年第3期226-233,共8页Current Biotechnology

基　　金：中国农业科学院基本科研业务基金项目(1610042018005)。

摘　　要：二氢槲皮素是自然界中一种重要的黄酮类化合物,主要存在于高寒带落叶松的根部。由于其具有较好的抗氧化、抗肿瘤等生物学活性而被广泛应用于食品领域、工业领域和医药领域。然而,目前二氢槲皮素的工业化生产仍然依赖于传统的植物提取,原料稀缺、提取难度大、产率较低,阻碍了其工业化应用的推进。基于此,主要综述了二氢槲皮素的化学结构及性质、生物合成的分子机制、生物学活性以及生产工艺的研究进展,并对未来二氢槲皮素的相关研究趋势进行了展望,以期为日后二氢槲皮素的生物合成研究提供理论参考。Dihydroquercetin is an important flavonoid compound in nature,which mainly exists in the root of Larix gmelinii in alpine zone.It has been widely used in food,industry and medicine fields due to its good biological activities such as anti-oxidation and anti-tumor.However,at present,the industrial production of dihydroquercetin still depends on traditional plant extraction,which is scarce in raw materials,difficult to extract and low in yield,thus hindering the advancement of its industrial application.Based on this,the research progress of chemical structure and properties,molecular mechanism of biosynthesis,biological activity and production technology of dihydroquercetin were mainly reviewed,and the related research trends in dihydroquercetin in the future were prospected,so as to provide theoretical references for the biosynthesis research on dihydroquercetin in the future.

关 键 词：二氢槲皮素 生物学活性 生产工艺 

分 类 号：R284[医药卫生—中药学]