NaBH4氢化合成3-苯基丙酸酯类化合物  

Synthesis of Phenyl 3-Phenylpropionate Compounds with NaBH4

作　　者：陈栋栋 白焱楠 张冉 侯思宇 Chen Dongdong;Bai Yannan;Zhang Ran;Hou Siyu(Department of Chemistry&Chemical Engineering,Lvliang University,Lvliang 033001;Datong University,Datong 037009,China)

机构地区：[1]吕梁学院化学化工系,山西吕梁033000 [2]山西大同大学化学与环境工程学院,山西大同037009

出　　处：《广东化工》2020年第11期25-26,共2页Guangdong Chemical Industry

摘　　要：论文讨论了以溴化亚铜为催化剂,硼氢化钠为氢源将肉桂酸酯氢化,合成3-苯基丙酸苯酯类化合物的工艺。考查了溶剂、反应温度、反应时间、催化剂比例和硼氢化钠比例对目标化合物收率的影响。实验发现最佳合成方法为:以无水甲醇为溶剂在0℃下,反应20 min,最佳物料比定为:肉桂酸酯∶溴化亚铜∶硼氢化钠=1.0∶0.5∶3.0。This paper discussed the process of synthesizing phenyl 3-phenylpropionate using cuprous bromide as catalyst and sodium borohydride as hydrogen source to hydrogenate cinnamate,and discussed the effects of solvent,reaction temperature,reaction time,catalyst ratio and sodium borohydride ratio on yields of target products.The experiment showed that the best synthesis method is:methanol as solvent at 0℃,stir for 20 minutes,the best material ratio is:cinnamate∶cuprous bromide∶Sodium borohydride=1.0∶0.5∶3.0.

关 键 词：3-苯基丙酸酯 氢化 溴化亚铜 

分 类 号：TQ[化学工程]