胸腹水结核斑点试验在诊断结核性胸膜炎中的临床价值  

Clinical Value of Hydrothorax Tuberculosis Pottest in Diagnosis of Tuberculous Pleurisy

作　　者：牟向欣 MU Xiang-xin(Department of Laboratory,Jinzhou Infectious Diseases Hospital,Jinzhou 121017,China)

机构地区：[1]辽宁省锦州市传染病医院检验科,辽宁锦州121017

出　　处：《中国医药指南》2020年第18期94-95,共2页Guide of China Medicine

摘　　要：目的探讨胸腹水结核斑点试验(T-SPOT.TB)在诊断结核性胸膜炎中的临床价值。方法回顾性分析2017年12月至2018年12月本院82例疑似结核性胸膜炎患者的临床资料,其中经活检病理检查确诊68例。均行胸腹水、外周血T-SPOT.TB检测。以病理结果为标准,比较胸腹水、外周血T-SPOT.TB诊断效果。结果本组患者经胸腹水T-SPOT.TB检出阳性率(81.71%)高于外周血T-SPOT.TB(68.29%)(P<0.05);以病理结果为标准,胸腹水T-SPOT.TB对结核性腹膜炎诊断敏感度、特异度、准确度分别为97.06%、92.86%、96.34%,高于外周血T-SPOT.TB的70.59%、42.86%、65.85%(P<0.05)。结论结核性胸膜炎诊断中应用胸腹水T-SPOT.TB可提升诊断敏感度、特异度及准确度,值得临床推广。Objective To investigate the clinical value of T-SPOT.TB in diagnosis of tuberculous Pleurisy.Methods Clinical data of 82 Patients with suspected tuberculous Pleurisy in our hospital from December 2017 to December 2018 were retrospectively analyzed,including 68 cases confirmed by biopsy and pathological examination.All cases were treated with pleural effusion and peripheral blood T-SPOT.TB.The diagnostic effect of T-SPOT.TB in pleural effusion and peripheral blood was compared.Results The positive rate of T-SPOT.TB was 81.71%,higher than that of T-SPOT.TB in peripheral blood(P<0.05);According to the pathological results,the diagnostic sensitivity,specificity and accuracy of T-SPOT.TB in pleural and ascites were 97.06%,92.86%and 96.34%,respectively,which were higher than 70.59%,42.86%and 65.85%of T-SPOT.TB in peripheral blood(P<0.05).Conclusion The application of T-SPOT.TB in the diagnosis of tuberculous pleurisy can improve the diagnostic sensitivity,specificity and accuracy,which is worthy of clinical promotion.

关 键 词：结核性胸膜炎 结核斑点试验 胸腹水 外周血 诊断 

分 类 号：R521.7[医药卫生—内科学]