高通量血液透析治疗终末期肾功能衰竭的临床疗效观察  

Clinical Observation of High-throughput Hemodialysis in the Treatment of End-stage Renal Failure

作　　者：丁傲 DING Ao(Jinzhou Central Hospital,Jinzhou 121000,China)

机构地区：[1]锦州市中心医院,辽宁锦州121000

出　　处：《中国医药指南》2020年第18期130-131,共2页Guide of China Medicine

摘　　要：目的探讨高通量血液透析治疗终末期肾功能衰竭的临床疗效。方法选择我院70例2017年2月至2018年9月终末期肾功能衰竭患者。随机分组,常规血液透析组采取常规血液透析治疗,高通量血液透析组则采取高通量血液透析治疗。比较两组疾病疗效;血清β2微球蛋白(β2-MG)的清除的水平;治疗前后患者血清尿素、肌酐、血清钙、血清碱性磷酸酶、血清白蛋白;不良反应。结果高通量血液透析组疾病疗效、血清β2微球蛋白(β2-MG)的清除的水平、血清尿素、肌酐、血清钙、血清碱性磷酸酶、血清白蛋白相比较常规血液透析组更好,P<0.05。高通量血液透析组不良反应瘙痒的发生率显著低于常规血液透析组,P<0.05。结论高通量血液透析治疗终末期肾功能衰竭可获得较好预后,可有效改善患者的肾功能以及缩短治疗的时间,有效改善患者的预后。Objective To investigate the clinical effi cacy of high-throughput hemodialysis in the treatment of end-stage renal failure.Methods 70 patients with end-stage renal failure were selected from February 2017 to September 2018.Random group,routine hemodialysis group to use routine hemodialysis treatment,high-throughput hemodialysis group to adopt high-throughput hemodialysis treatment.To compare the curative effect of two groups of diseases;The level of clearance of serumβ2 microglobulin(β2-MG);Serum urea,creatinine,serum calcium,serum alkaline phosphatase,serum albumin before and after treatment;Adverse reactions.Results The effi cacy of high-throughput hemodialysis group disease,the level of serumβ2 microglobulin(β2-MG)clearance,serum urea,creatinine,serum calcium,serum alkaline phosphatase,and serum albumin were better than those of conventional hemodialysis group.P<0.05.The incidence of adverse reactions to pruritus in high-throughput hemodialysis group was signifi cantly lower than that in conventional hemodialysis group,P<0.05.Conclusion high-throughput hemodialysis can improve the outcome of end-stage renal failure,improve renal function,shorten the treatment time and improve the prognosis.

关 键 词：高通量血液透析 终末期肾功能衰竭 临床疗效 

分 类 号：R692.5[医药卫生—泌尿科学]