探讨阿奇霉素序贯疗法对小儿肺炎支原体肺炎的疗效  

To Study the Effect of Achillomycin Sequence Therapy on Mycoplasma Pneumonia in Children

作　　者：刘石[1] LIU Shi(Shenyang Fourth People's Hospital,Shenyang 110000,China)

机构地区：[1]沈阳市第四人民医院,辽宁沈阳110000

出　　处：《中国医药指南》2020年第18期132-133,共2页Guide of China Medicine

摘　　要：目的探讨阿奇霉素序贯疗法对小儿肺炎支原体肺炎的疗效。方法选择我院80例2017年1月至2018年6月小儿肺炎支原体肺炎患者。随机分组,阿奇霉素静脉滴注治疗组采取阿奇霉素输液方法治疗,阿奇霉素序贯治疗组则采取阿奇霉素序贯疗法治疗。比较两组小儿肺炎支原体肺炎疗效;炎症控制的时间、病原体检查结果转阴时间;治疗前后患者肺部炎性因子指标超敏C反应蛋白、白细胞介素-6、白细胞计数、白细胞介素-8;不良作用。结果阿奇霉素序贯治疗组的治疗总有效率高于阿奇霉素静脉滴注治疗组的总有效率,P<0.05。阿奇霉素静脉滴注治疗组治疗显效14例,治疗有效16例,治疗无效10例,治疗总有效率是75%;而阿奇霉素序贯治疗组治疗显效25例,治疗有效15例,治疗无效0例,治疗总有效率是100%。阿奇霉素序贯治疗组小儿肺炎支原体肺炎炎症控制的时间、病原体检查结果转阴时间、肺部炎性因子指标超敏C反应蛋白、白细胞介素-6、白细胞计数、白细胞介素-8相比较阿奇霉素静脉滴注治疗组更好,P<0.05。阿奇霉素序贯治疗组和阿奇霉素静脉滴注治疗组不良作用相似,P>0.05。结论阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎效果好。Objective To investigate the effect of Achillomycin sequence therapy on Mycoplasma pneumonia in children.Methods 80 cases of Mycoplasma pneumonia were selected from January 2017 to June 2018.Random group,azithromycin intravenous drip treatment group took azithromycin infusion method treatment,azithromycin sequential treatment group took azithromycin sequence therapy treatment.To compare the curative effect of Mycoplasma pneumonia in children.Infl ammation control time,pathogen inspection results of the yin time;Before and after treatment,the pulmonary infl ammatory factor index was hypersensitive C reactive protein,interleukin-6,white blood cell count,interleukin-8;Bad effect.Results The total effi ciency of the treatment group was higher than that of the group treated with azithromycin intravenous drip,P<0.05.In the treatment group of azithromycin intravenous infusion,14 cases were treated,16 cases were effective,10 cases were ineffective,and the total effective rate of treatment was 75%.However,the total effective rate of treatment was 100%in 25 cases,15 cases were effective,and 0 cases were ineffective.Time of infl ammation control of Mycoplasma pneumoniae pneumonia in pediatric group,time of percolation of pathogen examination,hypersensitive factor index of pulmonary infl ammatory factor,interleukin-6,white blood cell count,interleukin-8 was better than that of azithromycin intravenous drip treatment group,P<0.05.The adverse effects of azithromycin in the sequential treatment group and azithromycin intravenous drip group were similar,P>0.05.Conclusion Achillomycin sequence therapy is effective in the treatment of Mycoplasma pneumonia in children.

关 键 词：阿奇霉素序贯疗法 小儿肺炎支原体肺炎 疗效 

分 类 号：R563.1[医药卫生—呼吸系统]