肺磨玻璃结节的诊断价值与处理策略  

Diagnostic value and treatment strategy of lung ground-glass nodules(GGNs)on CT

作　　者：吴心怡 蒋磊 吴伟 黄一心[3] WU Xin-Yi;JIANG Lei;WU Wei;HUANG Yi-xin(Department of Medical Imaging and Radiological Sciences,I-Shou University,Kaohsiung 84001,Taiwan,China)

机构地区：[1]台湾义守大学医学影像暨放射科学系,中国台湾高雄84001 [2]上海市华东疗养院 [3]江苏省寄生虫病防治研究所

出　　处：《中国校医》2020年第5期393-400,共8页Chinese Journal of School Doctor

摘　　要：肺癌是世界范围内患病率和死亡率最高的恶性肿瘤,其死亡率也是中国恶性肿瘤的第一位。早期诊断并妥善地治疗是防治肺癌的重要措施。随着诊疗技术水平的提高及其应用的普及,尤其是CT检查的普及,越来越多的病例被诊断出肺部磨玻璃结节(ground-glass nodule,GGN)。肺部GGN与肺癌的关系、其诊断价值与处理策略等已成为热门研究课题。本文主要对GGN的诊断价值与处理策略的研究做一综述,得出的主要结论为:健康体检者作CT检查,GGN的检出率在10%以上,女性较高,检出率随着年龄的增长而增加;GGN与肺癌的关系非常密切;低剂量CT能检出大部分肺部GGN,对身体基本无损伤,值得推广;经验丰富的放射科医师通过CT检出GGN的诊断已与病理学检查相当一致,说明CT检出GGN的诊断价值很大;处理策略上主要分为定期随访和积极治疗,未予手术者应定期准时随访,随访间隔因人而异,随访总体时间宜长不宜短,一旦发现明确的恶性征象应当及时终止随访转为积极治疗,治疗措施中以胸腔镜手术最为可靠,术后预后良好。文章还对今后的研究提出了建议。Now,the morbidity and mortality of lung carcinoma have been the highest among all the malignant tumors in the world,and in China,its mortality is the highest among all the malignant tumors.The early diagnosis and treatment are the important measures for lung carcinoma control.Along with the popularization of CT examinations,the patients found with lung ground-glass nodules(GGNs)are increasing day by day.The relationship between lung GGN and lung carcinoma,the diagnostic value of lung GGN on CT and its treatment strategy become hot research subjects.This article reviews the researches on the diagnostic value and treatment strategy of GGNs and obtains the main conclusions as following.Among the people who receive the physical examinations including thoracic CT,the detection rate of lung GGNs is above 10%,the rate in the female is higher than that in the male,and the rate increases with the age.The relationship between GGN and lung carcinoma is very associated.The low dose CT can find out most of lung GGNs and the examination almost does not hurt the body,therefore,it is worthy of popularization.The diagnosis of CT scans by the experienced radiologists is very consistent with the diagnosis of pathological examination,which means the diagnostic value of lung GGNs on CT is significant.The treatment strategy of lung GGNs mostly includes the regular follow-up mainly by chest CT and active treatment.The patients with lung GGNs who do not receive the surgery should be followed up at regular intervals,and the time of follow-up should be sufficiently long.Once the specific malignant signs are found,the follow-up should be stopped in time and the active treatment should begin.The most reliable treatment measure is thoracoscopic surgery,and after the surgery,the prognosis of the patient is very favorable.In addition,this article gives some suggestions of research subjects in the future.

关 键 词：肺癌 磨玻璃结节 诊断 

分 类 号：R563[医药卫生—呼吸系统]