碳酸银催化N-氟代二苯磺酰亚胺与丙炔酸衍生物的氢胺化反应  

Hydroamination of Propiolic Derivatives with N-Fluorobenzene-sulfonimide Catalyzed by Silver Carbonate

作　　者：任海平 田再文 李柯 张万轩 Ren Haiping;Tian Zaiwen;Li Ke;Zhang Wanxuan(Hubei Collaborative Innovation Center for Advanced Organic Chemical Material,Key Laboratory for the Synthesis and Application of Organic Functional Molecules,Ministry of Education,Hubei University,Wuhan 430062)

机构地区：[1]湖北大学有机化工新材料湖北省协同创新中心有机功能分子合成与应用教育部重点实验室,武汉430062

出　　处：《有机化学》2020年第5期1310-1315,共6页Chinese Journal of Organic Chemistry

基　　金：有机功能分子合成与应用教育部重点实验室资助项目(No.KLSAOFM1912).

摘　　要：N-氟代二苯磺酰亚胺(NFSI)的胺化反应已成为制备胺类化合物的重要方法,但利用它制备N-烯基磺酰亚胺的方法不多.在磷酸氢二钠存在下,碳酸银和1,10-菲啰啉衍生物共同催化NFSI与丙炔酸酯或丙炔酰胺发生氢胺化反应,高选择性地生成顺式N-烯基二苯磺酰亚胺类化合物,产率为35%~71%.Amination using N-fluorobenzenesulfonimide(NFSI)as nitrogen source has become an important route to prepare amines.However,there are few methods to prepare N-vinyl sulfonimides using NFSI as nitrogen source.In the presence of Na2HPO4,the hydroamination of propiolates or propiolamides with N-fluorobenzenesulfonimide(NFSI)was realized,where Ag2CO3 and 1,10-phenanthroline derivatives were added as catalysts.It leads to N-vinyldibenzenesulfonimides in high selectivity of Z isomers in the yields of 35%~71%.

关 键 词：碳酸银 N-氟代二苯磺酰亚胺 N-烯基二苯磺酰亚胺 丙炔酸酯 丙炔酰胺 

分 类 号：O623.73[理学—有机化学]