(E)-2-(甲氧基亚胺基)-2-甲基苯乙酸甲酯合成方法综述  

Review on Synthesis of(E)-2-(Methoxyimino)-2-methylphenylacetate

作　　者：吴长春 杨浩 董燕 王学玲 赵贵民 于海波 WU Chang-chun;YANG Hao;DONG Yan;WANG Xue-ling;ZHAO Gui-min;YU Hai-bo(State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Sinochem Agrochemicals R&D Co.,Ltd.,Shenyang 110021,China)

机构地区：[1]沈阳中化农药化工研发有限公司新农药创制与开发国家重点实验室,沈阳110021

出　　处：《农药》2020年第6期407-409,共3页Agrochemicals

摘　　要：(E)-2-(甲氧基亚胺基)-2-甲基苯乙酸甲酯(简称肟醚)是合成肟菌酯、烯肟菌胺、醚菌酯等甲氧基丙烯酸酯类杀菌剂的关键中间体,介绍了目前已报道的合成肟醚的各种合成路线,对其进行了初步评价,以期找到适合工业化的较佳合成工艺。(E)-2-(Methoxyimino)-2-methylphenylacetate(oxime ether for short)is the key intermediate for the synthesis of methoxyacrylate fungicides such as trifloxystrobin,fenaminstrobin and kresoxim-methyl,etc.Various synthetic routes of oxime ether reported at present were introduced and evaluated preliminarily in order to find suitable synthetic routes for industrialization.

关 键 词：肟醚 合成 工艺 

分 类 号：TQ460.3[化学工程—制药化工]