妊娠相关性暴发性1型糖尿病的研究进展  

Pregnancy-associated fulminant type 1 diabetes mellitus

作　　者：李汇[1] 崔瑾[1] 刘铭[1] Li Hui;Cui Jin;Liu Ming(Department of Endocrinology and Metabolism,Tianjin Medical University General Hospital,Tianjin 300052,China)

机构地区：[1]天津医科大学总医院内分泌代谢科,300052

出　　处：《中华全科医师杂志》2020年第5期455-458,共4页Chinese Journal of General Practitioners

基　　金：科技部重大研发项目(2019YFA0802502)。

摘　　要：妊娠相关性暴发性1型糖尿病是发生在妊娠期间或分娩后的暴发性1型糖尿病,其发病机制尚不明确,近年认为可能和免疫、病毒感染等相关。该病起病迅猛,多以糖尿病酮症酸中毒(DKA)为首发表现,预防或早期诊断难度大,胎儿预后差,故需要多个科室医师提高对本病的认识,及早诊断和治疗,改善孕妇和胎儿的预后。Pregnancy-associated fulminant type 1 diabetes mellitus(PF)is a subtype of fulminant type 1 diabetes mellitus(FT1DM)that occurs during pregnancy or perinatal period.Although it has been recently suggested that PF may be associated with viral infection and autoimmunity,the pathogenesis underlying this specific type of FT1DM remains largely unknown.PF usually develops and progresses very fast and its clinical outcome is poor.Increased awareness and knowledge of clinical features of PF,early diagnosis,and appropriated therapeutic intervention are the keys to improve clinical outcomes for both pregnant women and their babies.

关 键 词：糖尿病 1型 妊娠 糖尿病酮症酸中毒 

分 类 号：R714[医药卫生—妇产科学]