多索茶碱及高流量吸氧治疗老年呼吸衰竭患者的效果及对肺功能的影响  

Effect of doxofylline and high flow oxygen inhalation on elderly patients with respiratory failure and its influence on pulmonary function

作　　者：李小丽[1] 夏玉红[1] 陈亚飞[1] 张瑞[1] LI Xiao-li;XIA Yu-hong;CHEN Ya-fei;ZHANG Rui(No.2 Respiratory Department,Xinxiang Central Hospital,Xinxiang 453000,China)

机构地区：[1]新乡市中心医院呼吸二科,河南新乡453000

出　　处：《临床医学研究与实践》2020年第18期20-22,共3页Clinical Research and Practice

摘　　要：目的探讨多索茶碱及高流量吸氧治疗老年呼吸衰竭患者的效果及对肺功能的影响。方法将我院2017年5月至2019年5月收治的84例老年呼吸衰竭患者随机分为对照组(多索茶碱)和研究组(多索茶碱及高流量吸氧),各42例。比较两组的治疗效果。结果研究组的治疗总有效率高于对照组(P<0.05)。治疗后,两组的pH、PaCO2、RV/TLC及生活质量各项评分均降低,血氧饱和度、PaO2、OI、FEV1/FVC、DL-CO%、PEF25、TLC、PO2、PEmax均升高,且研究组优于对照组(P<0.05)。结论多索茶碱及高流量吸氧可有效改善老年呼吸衰竭患者的血气指标、肺功能指标,还可提高患者的临床疗效和生活质量。Objective To investigate the effect of doxofylline and high flow oxygen inhalation on elderly patients with respiratory failure and its influence on pulmonary function.Methods A total of 84 elderly patients with respiratory failure admitted in our hospital from May 2017 to May 2019 were randomly divided into control group(doxofylline)and study group(doxofylline and high flow oxygen inhalation),with 42 cases in each group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the study group was higher than that in the control group(P<0.05).After treatment,the pH,PaCO2,RV/TLC and quality of life scores of the two groups decreased,and the blood oxygen saturation,PaO2,OI,FEV1/FVC,DL-CO%,PEF25,TLC,PO2 and PEmax increased,and those in the study group were better than the control group(P<0.05).Conclusion Doxofylline and high flow oxygen inhalation can effectively improve blood gas indexes and pulmonary function indexes in elderly patients with respiratory failure,and also improve the clinical efficacy and quality of life of patients.

关 键 词：多索茶碱 高流量吸氧 呼吸衰竭 肺功能 

分 类 号：R563.8[医药卫生—呼吸系统]