苏黄止咳胶囊致四肢震颤  

Case Report Limbs tremor caused by Suhuang Zhike capsules(苏黄止咳胶囊)

作　　者：黄笑芳 龚丽娴 邓敏佳 杨晨 Huang Xiaofang;Gong Lixian;Deng Minjia;Yang Chen(Department of Pharmacy,General Hospital of Southern Theatre Command,Guangzhou 510010,China)

机构地区：[1]南部战区总医院药学部,广州510010

出　　处：《药物不良反应杂志》2020年第5期326-327,共2页Adverse Drug Reactions Journal

摘　　要：1例87岁女性高血压患者因咳嗽服用苏黄止咳胶囊3粒(每粒0.45 g)。服药0.5 h后,患者突然出现四肢震颤症状,伴心悸,大汗,持续约10 min左右自行缓解。患者血压145/79 mmHg(1 mmHg=0.133 kPa),神经系统检查未见异常,血糖、电解质、甲状腺功能、肝肾功能检查结果均正常,脑电图和头颅CT均无明显异常。考虑可能与苏黄止咳胶囊中的麻黄碱成分有关,停用该药,并给予阿普唑仑0.4 mg口服、2次/d,患者四肢震颤症状未再发作。An 87-year-old female patient with hypertension was given 3 Suhuang Zhike capsules(0.45 g/capsule)for cough.Half an hour after medication,the patient suddenly developed limbs tremor,accompanied by palpitation and sweating.The symptoms lasted for about 10 minutes and relieved spontaneously.Her blood pressure was 145/79 mmHg.Her nervous system examination showed no abnormality;blood glucose,electrolyte,thyroid function,and liver and kidney function were all normal;and electroencephalogram and cranial computed tomography showed no obvious abnormality.Ephedrine in Suhuang Zhike capsules was considered to be related to her symptoms.The drug was stopped and oral alprazolam 0.4 mg was given twice daily.The symptoms of limbs tremor did not recur in the patient.

关 键 词：麻黄 麻黄碱 震颤 

分 类 号：R2[医药卫生—中医学]