高胆固醇血症对心脏超声指标的影响  

Effect of hypercholesterolemia on cardiac ultrasound indicators

作　　者：米佳[1] 闫娟[1] 王佳强[1] Ml Jia;YAN Juan;WANG Jia-qiang(Department of Ultrasound,Yanan University Affiliated Hospital,Yanan Shaanxi 716000,China)

机构地区：[1]延安大学附属医院超声科,陕西延安716000

出　　处：《中国临床医学影像杂志》2020年第6期422-424,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨高胆固醇血症对患者心血管疾病发生的影响以及超声在患者心脏检查中的应用。方法:选取我院心血管内科2018年7月-2019年7月间收治的60例诊断为高胆固醇血症的患者作为研究对象,选取同时期60例血清胆固醇水平正常的患者作为对照组。采用超声检查两组患者心脏瓣膜是否存在狭窄和反流情况。检测两组患者心脏心室功能参数左心室高峰充盈率(Left ventricular peak filling rate,LVPER)和左心室射血分数(Left ventricular ejection fraction,LVEF)。检查两组患者主动脉根部内径和升主动脉内径。结果:高胆固醇血症组患者出现主动脉瓣反流(26.7%比8.3%)和狭窄(15.0%比3.3%)以及二尖瓣反流(18.3%比5.0%)和狭窄(11.7%比1.7%)的比例均显著高于对照组(P<0.05)。高胆固醇血症组患者LVPER((1.71±0.25)比(1.82±0.27))和LVEF((53.36±4.18)%比(55.47±4.72)%)均显著低于对照组(P<0.05)。高胆固醇血症组患者主动脉根部内径((35.37±3.92)mm比(32.17±3.64)mm)和升主动脉内径((34.91±3.71)mm比(31.64±4.52)mm)均显著高于对照组(P<0.05)。结论:高胆固醇血症能够对心脏瓣膜和主动脉功能产生影响,超声能够有效对心脏瓣膜和主动脉功能相关的疾病进行检查。Objective:To investigate the effects of hypercholesterolemia on cardiovascular disease and the application of ultrasound in patients’cardiac examination.Methods:Sixty patients diagnosed with hypercholesterolemia who were admitted to our department of cardiology from July 2018 to July 2019 were selected as subjects.Sixty patients with normal serum cholesterol levels were selected as the control group.Ultrasound was used to determine whether there was stenosis and reflux in the heart valves of the two groups of patients.Left ventricular peak filling rate(LVPER)and left ventricular ejection fraction(LVEF)were measured in the two groups.The aortic root diameter and the ascending aorta diameter were examined in both groups.Results:The proportion of aortic regurgitation(26.7%vs.8.3%)and stenosis(15.0%vs.3.3%)and mitral regurgitation(18.3%vs.5.0%)and stenosis(11.7%vs.1.7%)were significantly higher in the hypercholesterolemia group than in the control group(P<0.05).LVPER((1.71±0.25)vs.(1.82±0.27))and LVEF((53.36±4.18)%vs.(55.47±4.72)%)were significantly lower in the hypercholesterolemia group than in the control group(P<0.05).The diameter of the aortic root((35.37±3.92)mm vs.(32.17±3.64)mm)and the diameter of the ascending aorta((34.91±3.71)mm vs.(31.64±4.52)mm)were significantly higher in the hypercholesterolemia group than in the control group(P<0.05).Conclusion:Hypercholesterolemia can affect heart valve and aortic function,and ultrasonography can effectively check for heart valve and aortic function-related diseases.

关 键 词：高胆固醇血症 超声心动描记术 

分 类 号：R589.2[医药卫生—内分泌] R540.45[医药卫生—内科学]