正性心理暗示与杜冷丁在取卵术中的临床应用效果比较  

Comparison of clinical application effectiveness between positive psychological suggestion and dolantin on oocyte retrieval

作　　者：彭红 文宏贵[1] 罗红[1] 王丽[1] 游利英 谭长秀 Peng Hong;Wen Honggui;Luo Hong;Wang Li;You Liying;Tan Changxiu(Chongqing Institute of Reproductive and Genetic,Chongqing Health Center for Women and Children)

机构地区：[1]重庆市妇幼保健院遗传与生殖研究所,重庆400013

出　　处：《重庆医科大学学报》2020年第5期689-692,共4页Journal of Chongqing Medical University

摘　　要：目的:比较正性心理暗示与杜冷丁在体外受精-胚胎移植经阴道穿刺取卵术中的镇痛效果。方法:采用队列研究方法,将2018年在重庆市妇幼保健院遗传与生殖研究所进行首次体外受精-胚胎移植,年龄<37岁,无沟通交流障碍及药物过敏史,黄体期短效长方案进行控制性超排卵且卵泡数为5~15枚的患者1 307例,分为杜冷丁组680例(术前半小时肌内注射杜冷丁50 mg)和心理暗示组627例(术前半小时予正性心理暗示),比较2种方式下患者的术前焦虑评分、术中疼痛感及术后不良反应等。结果:心理暗示组患者术前焦虑评分低于杜冷丁组,差异有统计学意义(t=3.462,P=0.000),2组患者术中疼痛感差异无统计学意义(χ2=0.601,P=0.438);心理暗示组术后血压无下降,杜冷丁组患者术后血压下降明显,差异有统计学意义(t=-5.059,P=0.000);心理暗示组患者术后不良反应头晕、恶心、呕吐发生率低于杜冷丁组,差异有统计学意义(χ2=1181.762,P=0.000)。结论:在体外受精-胚胎移植经阴道穿刺取卵术前给予患者正性心理暗示,可减少患者焦虑情绪,达到与使用杜冷丁相同的镇痛效果,有效避免因杜冷丁引起的药物不良反应。Objective:To compare the analgesic effect of positive psychological suggestion and dolantin injection in in vitro fertilization-embryo transfer(IVF-ET) via vaginal puncture. Methods:A total of 1 307 patients,with age less than 37 years old and without communication barrier and drug allergy history,who experienced controlled ovarian hyperstimulation in luteal phase throuth the shortterm-effect long strategy and had 5-10 ovarian follicles,and experienced the IVF-ET in our department in 2018 were selected and divided into the dolantin group of 680 patients(intramuscularly injecting dolantin of 50 mg before 30 minutes of operation) and the psychological suggestion group of 627 patients(positive psychological suggestion before 30 minutes of operation). Pre-operative anxiety score,intraoperative pain and post-operative adverse reactions were compared between two groups. Results:The anxiety score in the psychological suggestive group was lower than that in the dolantin group,with statistically significant difference(t=3.462,P=0.000),and there was no significant difference in pain feeling between two groups( χ2=0.601,P=0.438). Post-operative blood pressure in the psychological suggestion group was not decreased,but it was significantly decreased in the dolantin group(t=-5.059,P=0.000). The incidence rate of dizziness,nausea and vomiting in the psychological suggestion group was lower than that in the dolantin group,with staitistically significant difference(χ2=1181.762,P=0.000). Conclusion:Before the IVF-ET to give positive psychological suggestion to patients can reduce anxiety,obtain same analgesic effect with dolantin,and effectively avoid adverse drug reactions caused by dolantin.

关 键 词：体外受精-胚胎移植 取卵术 正性心理暗示 杜冷丁 镇痛 

分 类 号：R47[医药卫生—护理学]