空间频域成像在皮肤病定量评估中的研究  

Application of spatial frequency domain imaging in quantitative evaluation of skin diseases

作　　者：曹自立[1,3] 陈新林 潘达 苗丹[2] 曾碧新 CAO Zili;CHEN Xinlin;PAN Da;MIAO Dan;ZENG Bixin(School of Biomedical Engineering,Wenzhou Medical University,Wenzhou 325035,China;School of Ophthalmology and Optometry,Wenzhou Medical University,Wenzhou 325035,China;Institute of Lasers and Biomedical Photonics,Wenzhou Medical University,Wenzhou 325035,China)

机构地区：[1]温州医科大学生物医学工程学院,浙江温州325035 [2]温州医科大学眼视光学院,浙江温州325035 [3]温州医科大学激光与光子生物医学研究所,浙江温州325035

出　　处：《中国医学物理学杂志》2020年第6期714-719,共6页Chinese Journal of Medical Physics

基　　金：温州市科技计划项目/公益性社会发展科技项目(S20170007);浙江省自然科学基金公益技术研究计划项目(LGF18H180013)。

摘　　要：利用空间频域成像技术搭建的成像系统检测多种皮肤病组织的光学参数和生理参数信息,并对比分析讨论不同类型的皮肤病与光学参数、生理参数之间的关系。实验结果表明,病变皮肤组织与正常皮肤组织之间在光学参数、生理参数上存在较大差异,这将为临床医生对皮肤病诊治提供一种新颖、可靠、科学的评估方法。The optical and physiological parameters from various diseased skin tissues are detected and categorized by spatial frequency domain imaging technology,and the relationships between different types of skin diseases and the optical and physiological parameters are discussed.The experimental results show that there are significant differences in the optical and physiological parameters between the diseased skin tissues and the normal skin tissues.Spatial frequency domain imaging technology is proved to be a novel,reliable and scientific method for the clinical diagnosis and treatment of skin diseases.

关 键 词：空间频域成像 皮肤病 光学参数 生理参数 定量评估 

分 类 号：R318.6[医药卫生—生物医学工程]