关节置换手术患者假体感染的影响因素  

Influencing factors for prosthetic infection in patients undergoing joint replacement surgery

作　　者：张金辉[1] 王健 吴铮 解光越 王跃新[1] ZHANG Jin-hui;WANG Jian;WU Zheng;XIE Guang-yue;WANG Yue-xin(Tangshan Workers′Hospital,Tangshan,Hebei 063000,China)

机构地区：[1]唐山市工人医院骨科,河北唐山063000 [2]唐山市工人医院介入科,河北唐山063000 [3]唐山市工人医院肝胆外科,河北唐山063000

出　　处：《中华医院感染学杂志》2020年第9期1373-1376,共4页Chinese Journal of Nosocomiology

基　　金：河北省卫生厅科研基金资助项目(20150804)。

摘　　要：目的分析关节置换手术患者术后假体感染的影响因素,为降低术后感染提供临床依据。方法选取2015年6月-2018年9月于唐山市工人医院接受初次全髋和全膝关节置换术的244例患者为研究对象,按照术后是否出现假体感染将患者分为两组,96例假体感染患者为假体感染组,148例未出现假体感染的患者为非假体感染组。回顾性分析患者性别、病程、手术时间、吸烟史、合并代谢综合征等临床资料,单因素及多因素Logistic回归分析关节置换术患者出现假体感染的影响因素。pearson相关性分析代谢综合征与假体感染的相关性。结果单因素分析结果显示,两组患者的性别、病程以及手术时间比较无显著差异,假体感染组患者年龄(52.13±6.39)岁高于非假体感染组(P<0.05),假体感染组吸烟史、合并代谢综合征及炎性关节炎患者占比均显著高于非假体感染组(P<0.05)。多因素Logistic回归分析结果,合并代谢综合征是关节置换手术患者假体感染的独立影响因素(P<0.05)。代谢综合征与假体感染呈正相关关系(P<0.05),代谢综合征越严重,关节置换患者假体感染的可能性越高。结论代谢综合征是关节置换手术患者假体感染的独立影响因素,代谢综合征越严重,关节置换术患者发生假体感染的可能性越大。OBJECTIVE To investigate the influencing factors for postoperative prosthetic infection in patients undergoing joint replacement surgery so as to provide clinical basis for reduction of incidence of postoperative infection.METHODS A total of 244 patients who received primary total hip and total knee arthroplasty in Tangshan Workers′Hospital from Jun 2015 to Sep 2018 were recruited as the study objects and divided into two groups according to the status of postoperative prosthetic infection,96 patients who had prosthetic infection were assigned as the prosthetic infection group,and 148 patients who did not have prosthetic infection were set as the non-prosthetic infection.The clinical data,including the gender,course of disease,operation duration,smoking history and complication with metabolic syndrome,were retrospectively analyzed;univariate analysis and multivariate logistic regression analysis were performed for influencing factors for the prosthetic infection in the patients undergoing joint replacement surgery,and the correlation between the metabolic syndrome and the prosthetic infection was observed by means of pearson analysis.RESULTS The result of univariate analysis showed that there were no significant differences in gender,course of disease and operation duration between the two groups of patients,the patients of the prosthetic infection group(52.13±6.39)years old were significantly older than the patients of the non-prosthetic infection group(P<0.05),the proportions of the patients who had smoking history,complication with metabolic syndrome and inflammatory arthritis were significantly higher in the prosthetic infection group than in the non-prosthetic infection group(P<0.05).Multivariate logistic regression analysis indicated that the complication with metabolic syndrome was the independent influencing factor for the prosthetic infection in the patients undergoing joint replacement surgery(P<0.05).The metabolic syndrome was positively correlated with the prosthetic infection(P<0.05),the severer t

关 键 词：关节置换 假体感染 代谢综合征 影响因素 

分 类 号：R687.4[医药卫生—骨科学]