红外光谱法测定大连地区1761例泌尿系结石成分分析  

Clinical analysis of the composition of urinary calculus in 1761 cases in Dalian by infrared spectroscopy

作　　者：陶胜华 王炜[2] 王群[2] 沈宸[2] 范博 王小刚 陈志岐 于娜[2] 李先承[2] TAO Shenghua;WANG Wei;WANG Qun;SHEN Chen;FAN Bo;WANG Xiaogang;CHEN Zhiqi;YU Na;LI Xiancheng(Dalian Medical University,Dalian 116044,China;Department of Urology,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China)

机构地区：[1]大连医科大学第二临床学院,辽宁大连116044 [2]大连医科大学附属第二医院泌尿外科,辽宁大连116027

出　　处：《大连医科大学学报》2020年第3期198-201,214,共5页Journal of Dalian Medical University

基　　金：国家自然科学基金项目(81972831)。

摘　　要：目的探讨大连地区泌尿系结石的成分组成,为临床防治提供依据。方法收集2017年3月至2019年12月共1761例结石标本,包括男性1140例,女性621例,年龄7个月~93岁,上尿路结石1626例,下尿路结石135例。采用红外光谱分析法分析结石成分,比较不同年龄段患者在性别及结石位置上的差异。结果男性高发;高发年龄段为51~70岁,该年龄段患者占所有患者的60%以上;一水草酸钙检出率最高为75.87%,其次为碳酸磷灰石45.26%;单纯型结石761例(43.21%),混合型结石1000例(56.79%)。结论大连地区泌尿系结石成分以草酸钙为主,混合结石多于单纯结石,给予个体化生活指导建议有利于本地泌尿系结石的防治。Objective The composition of urinary calculi in Dalian area was preliminarily discussed to provide a basis for clinical prevention and treatment.Methods A total of 1761 stone specimens were collected from 1140 males and 621 females between March 2017 and December 2019.The patients'age ranged from 7 months to 93 years-old.Most of the stones were obtained from the upper urinary tract(1626/1761).The components of calculi were analyzed by infrared spectroscopy.Results Most of the patients were men,with a male-to-female ratio of 1.68.Upper urinary calculi were more common.The age group with high incidence was 51 to 70 years-old,which accounted for more than 60%of all patients.The detection rate of calcium oxalate monohydrate was the highest(75.87%),followed by carbonate apatite(45.26%).There were 761 cases of simple calculi(43.21%)and 1000 cases of mixed calculi(56.79%).Conclusions The composition of urinary calculi in Dalian area was mainly calcium oxalate,and mixed calculi were more common than simple calculi.Individualized life guidance is helpful for the prevention and treatment of urinary calculi locally.

关 键 词：泌尿系结石 结石分析 复发 

分 类 号：R691[医药卫生—泌尿科学]