填埋龄对填埋垃圾中抗生素残留特征的影响  

Effects of Landfill Age on the Characteristics of Antibiotic Residues in Landfill Waste

作　　者：张治川 许赛 叶蓉 冯优 陈飞宇 陆文静[2] Zhang Zhichuan;Xu Sai;Ye Rong;Feng You;Chen Feiyu;Lu Wenjing(College of Environmental and Biological Engineering,Nanjing University of Science and Technology,Nanjing Jiangsu 210094;College of Environment,Tsinghua University,Beijing 100084;Jiangsu University Key Laboratory of Chemical Pollution Control and Resources Reuse,Nanjing Jiangsu 210094)

机构地区：[1]南京理工大学环境与生物工程学院,江苏南京210094 [2]清华大学环境学院,北京100084 [3]江苏省化工污染控制与资源化高校重点实验室,江苏南京210094

出　　处：《环境卫生工程》2020年第3期55-59,共5页Environmental Sanitation Engineering

基　　金：环境模拟与污染控制国家重点联合实验室专项经费资助项目(20K06ESPCT);江苏省大学生创新创业训练计划项目(201910288110Y)。

摘　　要：为探究不同填埋龄的填埋垃圾中抗生素残留特征,采集了北京阿苏卫填埋场中老龄填埋区和新鲜填埋区的填埋垃圾样品,采用超高效液相色谱-三重四极杆串联质谱仪分析了填埋垃圾中5类14种抗生素的浓度。结果显示,四环素类、磺胺类、大环内酯类、β-内酰胺类和喹诺酮类抗生素浓度范围为26.6~288.4、65.1~148.6、17.4~94.2、9.1~102.2、173.6~468.6μg/kg。喹诺酮类抗生素氧氟沙星浓度最高,平均浓度达到240.0μg/kg,占全部抗生素浓度的52.0%。老龄填埋区中抗生素浓度显著低于新鲜填埋区中(P<0.01),这可能与填埋垃圾组分以及填埋过程的微生物降解有关。To explore the characteristics of antibiotic residues in landfill waste of different landfill ages,landfill waste samples were collected from the old landfill area and the fresh landfill area of Beijing Asuwei landfill site.The ultra-high performance liquid chromatography combined with triple four-bar tandem mass spectrometry was adopted to analyze the concentrations of 14 antibiotics from 5 classes in landfill waste.The results showed that the antibiotics concentrations of tetracyclines,sulfonamides,macrolides,β-lactam and quinolones ranged from 26.6 to 288.4μg/kg,65.1 to 148.6μg/kg,17.4 to 94.2μg/kg,9.1 to 102.2μg/kg,173.6 to 468.6μg/kg,respectively.The ofloxacin belonged to quinolones had the highest concentration with an average concentration of 240.0μg/kg,which accounted for 52.0%of the total antibiotic concentration.The concentration of antibiotics in the aged landfill was significantly lower than that in the fresh landfill(P<0.01),which may be related to the composition of landfill waste and the microbial degradation during landfill.

关 键 词：抗生素 填埋龄 垃圾 填埋场 

分 类 号：R978.1[医药卫生—药品] X799.3[医药卫生—药学]