职业性急性甲醇中毒5例  

Clinical analysis of 5 cases of occupational acute methanol poisoning

作　　者：张明浩 任彬 赵顺忠 王伯良 Zhang Minghao;Ren Bin;Zhao Shunzhong;Wang Boliang(Department of Emergency,the Second Affiliated Hospital of Air Force Military Medical University,Xi'an 710038,China)

机构地区：[1]空军军医大学第二附属医院急诊科,西安710038

出　　处：《中华劳动卫生职业病杂志》2020年第5期378-380,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：目的探讨职业性急性甲醇中毒的诊断分级和救治方法。方法回顾性分析2018年10月11至12日我院收治的5例职业性急性甲醇中毒患者的临床资料。结果患者1诊断为重度急性甲醇中毒,给予机械通气、血液透析,以及乙醇与叶酸解毒等治疗38 h后死亡。其他4例诊断为轻度急性甲醇中毒,经积极对症支持治疗63~69 h后好转出院,随访近一年无后遗症。结论尽早准确评估病情,早期联合血液透析和应用解毒药物是救治职业性急性甲醇中毒的关键。Objective To investigate the diagnosis and treatment of occupational acute methanol poisoning.Methods Retrospective analysis of the clinical data of 5 cases of occupational acute me thanol poisoning admitted from October 11 to 12,2018.Results The first patient was diagnosed with severe acute methanol poisoning and died after treatment with mechanical ventilation,hemodialysis,and detoxification by ethanol and folic acid for 38 hours.The remaining four cases were all diagnosed with mild acute methanol poisoning and were discharged from hospital after active symptomatic support treatment for 63 to 69 hours.Fuhermore,all the four patients were followed up for one year and without sequelaes.Conclusion Early evaluation of the disease,early combination with hemodialysis,and use of detoxification drugs are the key to rescue occupational acute methanol poisoning.

关 键 词：甲醇 代谢性酸中毒 血液透析 

分 类 号：R135.1[医药卫生—劳动卫生]