腹腔镜下腹股沟疝修补术对手术效果及T淋巴细胞百分比的影响  

Impact of laparoscopic inguinal hernia repair on surgical effect and T lymphocyte percentage

作　　者：吴世乐[1] 宋世铎[2] 赵克昌[1] 朱文君 杨金煜[1] Shi-le Wu;Shi-duo Song;Ke-chang Zhao;Wen-jun Zhu;Jin-yu Yang(Department of General Surgery,Qinghai Provincial People’s Hospital,Xi’ning,Qinghai 810000,China;Department of General Surgery,the First Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215006,China)

机构地区：[1]青海省人民医院普外科,青海西宁810000 [2]苏州大学附属第一医院普外科,江苏苏州215006

出　　处：《中国内镜杂志》2020年第6期20-24,共5页China Journal of Endoscopy

摘　　要：目的探讨腹腔镜下腹股沟疝修补术对手术效果及T淋巴细胞百分比的影响。方法选取2017年1月-2019年1月腹股沟疝患者280例作为研究对象,随机分为对照组(n=140)和观察组(n=140)。对照组采用开放无张力疝修补术,观察组采用腹腔镜下无张力疝修补术,术后7 d对患者治疗效果进行评估,比较两组手术指标、疼痛视觉模拟评分(VAS)、T淋巴细胞百分比及术后并发症。结果观察组与对照组手术时间比较,差异无统计学意义(P>0.05);观察组出血量、术后自主活动时间及VAS评分少于对照组(P<0.05);观察组治疗费用多于对照组(P<0.05);观察组手术后7 d CD3^+、CD4^+和CD4^+/CD8^+百分比高于对照组(P<0.05);观察组手术后7 d CD8^+百分比低于对照组(P<0.05);观察组手术后切口疼痛、尿潴留、阴囊水肿及切口感染发生率与对照组比较,差异均无统计学意义(P>0.05)。结论将腹腔镜手术用于腹股沟疝患者中,手术创伤较小,能改善患者T淋巴细胞百分比,未增加术后并发症发生率,值得推广应用。Objective To investigate the impact of laparoscopic inguinal hernia repair on the surgical effect and T lymphocyte percentage.Methods From January 2017 to January 2019,280 patients with inguinal hernia were selected as subjects and randomly divided into control group(n=140)and observation group(n=140).The control group used open tension-free hernia repair,and the observation group used laparoscopic tension-free hernia repair.The patient’s effect was evaluated 7 days after surgery.The surgical indicators,visual pain simulation score(VAS),percentage of T lymphocytes,and postoperative complications.Results There was no significant difference in the operation time between the two groups(P>0.05).The amount of bleeding,postoperative autonomic activity time and VAS score in the observation group were less(lower)than those in the control group(P<0.05).More than the control group(P<0.05);The percentage of CD3^+,CD4^+,CD4^+/CD8^+7 days after surgery in the observation group was higher than that in control group(P<0.05);The percentage of CD8^+7 days after surgery in the observation group was lower than that in control group(P<0.05);The incidence of incision pain,urinary retention,scrotal edema,and incision infection in the observation group was not statistically significant compared with the control group(P>0.05).Conclusion Laparoscopic surgery is less invasive in patients with inguinal hernia,which can improve the percentage of T lymphocytes in patients and does not increase the incidence of postoperative complications.It is worth of popularizing and applying.

关 键 词：腹股沟疝 腹腔镜手术 T淋巴细胞百分比 临床指标 

分 类 号：R656.21[医药卫生—外科学]